Abstract: SA-PO275
Prevalence of Kidney Stones in the United States over the Past 10 Years
Session Information
- Bone and Mineral Metabolism: Calcium, Magnesium, Kidney Stones
November 09, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Bone and Mineral Metabolism
- 402 Bone and Mineral Metabolism: Clinical
Authors
- Chewcharat, Api, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States
- Curhan, Gary C., Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States
Background
Kidney stones (KS) are common in the US and cost billions of dollars on treatment. The overall prevalence of kidney stones rose from 3.2% in 1980 to 10.1% in 2014. We examined the prevalence trends of KS in subgroups of age, sex and race in the US and identify laboratory factors associated with a history of KS using National Health and Nutrition Examination Survey (NHANES) data
Methods
We conducted a cross-sectional study among 28,209 US adults aged >=10 years old in the NHANES from 2007 to 2016. We calculated the percent prevalence of a self-reported history of KS by using weights and standardized to the 2010 US Census population using age adjustment. We also analyzed relevant laboratory values and compared them according to history of KS.
Results
The prevalence of KS decreased from 8.8% in 2007-2008 to 8.6% in 2009-2010 and 7.2% in 2011-2012 but then increased to 9.0% in 2013-2014 and 10.2% in 2015-2016. Prevalence of KS was highest in 2015-2016 in every age range except in women aged 20-39 years. Among different races, non-Hispanic whites had the highest prevalence of KS at 12.1% for the last cycle of 2015-2016 and the trend was increasing from 2011-2016. Non-Hispanic Asians had the lowest prevalence of KS at 4.5% for the last cycle. The prevalence of KS among non-Hispanic blacks increased over the last 3 cycles from 4.2% in 2011-2012 to 5.0% in 2013-2014 and 5.7% in 2015-2016. We presented relevant laboratory values in Figure 1.
Conclusion
Overall prevalence of KS has been increasing for the last 6 years but this may be random variability as the prevalence decreased then increased since 2007-2008. Men had higher prevalence of KS and Asians had the lowest prevalence. Stone formers had lower urine flow rate, eGFR, bicarbonate, phosphate, serum estrogen and testosterone while they had higher serum osmolality, creatinine, chloride and uric acid compared with non-stone formers.