ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on Twitter

Kidney Week

Abstract: FR-PO1035

Number of Right Coronary Artery Lesions Increases as CKD Progresses

Session Information

Category: Hypertension and CVD

  • 1402 Hypertension and CVD: Clinical, Outcomes, and Trials

Author

  • Gen, Shiko, Saitama Sekishinkai Hospital, Sayama city, Japan
Background

Chronic kidney disease is a risk factor for cardiovascular disease, and low glomerular filtration rate (GFR) is known to be associated with a higher risk of developing cardiovascular disease. However, there is currently no report on the association between the stage of chronic kidney disease and coronary artery lesion parameters such as site and number.

Methods

We examined variations in the site and number of coronary artery lesions in relation to the presence or absence of diabetes and dyslipidemia, and differences in laboratory parameter values such as serum blood urea nitrogen (BUN), creatinine (Cr), and estimated glomerular filtration rate (eGFR) in 2885 cases (average age: 68.96±10.32 years; 2140 men, 745 women) who underwent coronary angiography in our hospital from January 2009 to November 2011.

Results

Although there was no significant variation in coronary artery lesion sites in relation to differences in age or the presence or absence of diabetes or dyslipidemia, there was a significant increase in the number of right coronary artery lesions as the stage of chronic kidney disease progressed (P=0.001, Kruskal Wallis test).

Conclusion

Our results suggest that the progression of renal dysfunction may cause an increase in the number of right coronary artery lesions.