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Abstract: TH-PO289

Incremental Peritoneal Dialysis and Clinical Outcomes: A Propensity Score Matching Study

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis

Authors

  • Lee, Su mi, Dong-A University, Busan, Busan, Korea (the Republic of)
  • Oh, Yun Jung, Cheju Halla General Hospital, Jeju, Korea (the Republic of)
  • Son, Young ki, Cheju Halla General Hospital, Jeju, Korea (the Republic of)
  • Kim, Seong Eun, Dong-A University, Busan, Busan, Korea (the Republic of)
  • An, Won Suk, Dong-A University, Busan, Busan, Korea (the Republic of)
Background

Incremental peritoneal dialysis (iPD) can be useful in selected patients with higher residual renal function, needing lower financial cost, or wanting less time burden of PD treatment. In addition, patients on iPD would have a reduced risk of peritonitis or peritoneal glucose exposure. However, the long-term effects of iPD on patient survival and PD survival are not clear compared to conventional PD (cPD). The aim of this study to evaluate the patient survival and PD survival in iPD compared to cPD.

Methods

Clinical data was retrospectively collected from a single center between January 2007 and December 2018. We included 303 patients percutaneously inserted PD catheter by surgical methods. An analysis was performed using propensity score matching for age, gender, and the presence of DM. Finally, 96 cPD patients and 48 iPD patients were included. IPD was defined as starting PD with 3 or fewer peritoneal exchanges per day.

Results

Median duration of iPD was 31.2±22.5 months and mean PD duration of iPD was longer than cPD. Initial blood urea nitrogen and serum creatinine levels (7.3±2.7 vs. 9.7±3.7 mg/dL, p <0.001) were significantly lower in iPD patients than cPD patients. Mortality as well as rates of peritonitis and hospitalization was significantly lower in patients with iPD than those with cPD (log-rank, p=0.034, p=0.001 and p=0.023). Mortality and hospitalization rate were prominent in cPD patients with diabetes. However, there was no significant difference in PD survival between iPD and cPD.

Conclusion

Incremental PD may be not only safe PD modality but also has better clinical outcome in less uremic patients to initiate and maintain PD. Further prospective studies are necessary to confirm these benefits in diabetic patients treated with PD.