Abstract: TH-PO687
Can Central Blood Pressure Be Accurately Estimated in Individuals with and Without Systolic Blood Pressure Amplification?
Session Information
- Hypertension and CVD: Epidemiology, Risk Factors
November 07, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Hypertension and CVD
- 1401 Hypertension and CVD: Epidemiology, Risk Factors, and Prevention
Authors
- Goupil, Remi, Hopital du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
- Lamarche, Florence, Hopital du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
- Kowalski, Cédric, Hopital du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
Background
Systolic blood pressure (SBP) does not always amplify from central to peripheral arteries. Individuals without SBP amplification (SBPamp) have higher aortic blood pressure (BP) despite similar brachial cuff SBP. To circumvent this discrepancy, the aim of this study was to determine if aortic SBP can be accurately estimated non-invasively in patients with and without SBPamp.
Methods
Patients undergoing non-urgent percutaneous coronary angiogram were recruited. Individuals with atrial fibrillation, ≥10 mmHg between-arm SBP difference or severe aortic stenosis were excluded. After the procedure, aortic and brachial intra-arterial BP were measured via radial artery approach using a fluid-filled catheter. Simultaneously, brachial and central cuff BP were measured in triplicate using a Mobil-o-Graph (IEM, Germany). This device estimates central BP via brachial pulse wave analysis by type I (SBP and diastolic BP) and type II (mean and diastolic BP) calibrations. Aortic-to-brachial SBPamp was defined as ≥5 mmHg increase between intra-arterial aortic and brachial SBP.
Results
Of the 151 patients recruited, only 85 had SBPamp. SBPamp+ and SBPamp- patients had similar characteristics, apart from higher augmentation in SBPamp- (Table 1). Central BP estimated with Type I or Type II calibration could not accurately determine aortic SBPs in both phenotypes (Table 2). Using the mean of both estimates only provided a slightly better accuracy.
Conclusion
Central BP measurements cannot identify the different aortic BP of the SBPamp phenotypes. A new central BP calibration may be needed to circumvent this problem.
Table 1
Table 2