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Abstract: TH-PO186

Thoracic Electrical Bioimpedance Measurement in Monitoring Cardiac Index and Thoracic Fluid Content During Hemodialysis

Session Information

Category: Dialysis

  • 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Wu, Jining, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China
  • Xu, Zhuo, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China
  • Ye, Hong, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China
  • Yang, Junwei, Second Affiliated Hospital, Nanjing Medical University, Nanjing, China
Background

Hemodynamic stress during hemodialysis (HD) results in recurrent segmental ischemic injury that drives cumulative cardiac damage. Thoracic electrical bioimpedance (TEB) has been shown to provide accurate, noninvasive, continuous, measurements of cardiac index (CI) and thoracic fluid content (TFC).We performed this study to evaluate the changes in TFC in comparison with fluid removal (FR) and to understand the trends in CI changes in HD patients.

Methods

In this observational study, we enrolled 114 patients from a single hemodialysis unit. Minute-by-minute changes in TFC and CI were collected using the TEB (BioZ) in HD patients. Change in body weight (DW) and amount of FR were measured.

Results

The TFC decreased in all patients by an average of 4.6±2.4 1/kΩ, weight decreased by 2.05±1.12kg, and FR averaged 2.5±0.98 L in HD session. There were good correlations between change in TFC and DW (R=0.74, P<0.001) and FR (R=0.82, P<0.001). A 1/kΩ change of TFC correlates with an 150mL change in total body water. The change in CI (-0.42 ±0.51L/min/m2) during HD did not correlate with FR (R=0.14, P=NS). Changes in TFC represented the monitored variable most closely related to FR. Interestingly, during the first 5 mins of HD, CI and stroke volume index reduced obviously compared to the base lever before dialysis.

Conclusion

It suggested that thoracic electrical bioimpedance could monitor the acute cardiac effects of dialysis during hemodialysis treatment.

Funding

  • Government Support - Non-U.S.