ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on Twitter

Kidney Week

Abstract: TH-PO241

Symptom Burden in Renal Patients Under the Care of Single United Kingdom Center

Session Information

Category: Dialysis

  • 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Gullapudi, Venkata Rukmini Latha, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
  • Chauhan, Komal, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
  • Dukka, Hari, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
Background

Renal patients suffer from a high and variable symptom burden, irrespective of the standard of care provided. We assessed the symptom burden of a cohort of renal patients under our care to understand the extent of the problem in our center.

Methods

NHS England health survey questionnaire was used to evaluate symptoms suffered by patients with chronic kidney disease (CKD) stage 4/5 and those receiving renal replacement therapy (RRT). Age, Urea clearances, Charlson comorbidity index (CCI), eGFR and RRT vintage were noted.

Results

290 patients completed the questionnaire. Median age was 64.5 (IQR: 21), 60.3% were males with median CCI of 3.5 (IQR: 6) .The whole cohort experienced a median of 3.5/17 symptoms (IQR: 6). Weakness (53.45%), poor mobility (40.69%) and difficulty sleeping (33.96%) were the top 3 symptoms complained. Table 1 summaries the distribution and top 3 symptoms suffered by patients with CKD and those on RRT. Symptom burden was significantly less in the transplant cohort.
Age, renal clearances (eGFR in CKD and tranplant cohorts; Kt/V in dialysis cohorts) did not correlate with symptom burden, however CCI score statistically (r=0.193, p=0.001) correlated to the symptom burden.

Conclusion

Renal patients experience multitude of symptoms and symptom burden is similar in CKD and those on RRT.The standards of care provided to renal patients should include symptom assessment and management where possible.

Table 1
 CKD
N=63
Haemodialysis
N=111
Home therapies
N=49
Transplant
N=67
Median number of symptoms experienced*4 (IQR: 7)5 (IQR: 6)4 (IQR: 5)1 (IQR: 4)
1st most common
Symptom and % experiencing
Weakness
50.8%
Weakness
63.96%
Weakness
55.10%
Weakness
37.31%
2nd most common
Symptom and % experiencing
Poor Mobility
38.1%
Poor Mobility
57.66%
Poor Mobility
40.81%
Difficulty Sleeping
31.34%
3rd most common
Symptom and % experiencing
Difficulty Sleeping
38.1%
Difficulty Sleeping
43.24%
Difficulty Sleeping
40.81%
Feeling anxious &
Shortness of Breath
20.9%

*Questionnaire explored 17 symptoms in total