Abstract: TH-PO241
Symptom Burden in Renal Patients Under the Care of Single United Kingdom Center
Session Information
- Hemodialysis and Frequent Dialysis - II
November 07, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Gullapudi, Venkata Rukmini Latha, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
- Chauhan, Komal, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
- Dukka, Hari, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, United Kingdom
Background
Renal patients suffer from a high and variable symptom burden, irrespective of the standard of care provided. We assessed the symptom burden of a cohort of renal patients under our care to understand the extent of the problem in our center.
Methods
NHS England health survey questionnaire was used to evaluate symptoms suffered by patients with chronic kidney disease (CKD) stage 4/5 and those receiving renal replacement therapy (RRT). Age, Urea clearances, Charlson comorbidity index (CCI), eGFR and RRT vintage were noted.
Results
290 patients completed the questionnaire. Median age was 64.5 (IQR: 21), 60.3% were males with median CCI of 3.5 (IQR: 6) .The whole cohort experienced a median of 3.5/17 symptoms (IQR: 6). Weakness (53.45%), poor mobility (40.69%) and difficulty sleeping (33.96%) were the top 3 symptoms complained. Table 1 summaries the distribution and top 3 symptoms suffered by patients with CKD and those on RRT. Symptom burden was significantly less in the transplant cohort.
Age, renal clearances (eGFR in CKD and tranplant cohorts; Kt/V in dialysis cohorts) did not correlate with symptom burden, however CCI score statistically (r=0.193, p=0.001) correlated to the symptom burden.
Conclusion
Renal patients experience multitude of symptoms and symptom burden is similar in CKD and those on RRT.The standards of care provided to renal patients should include symptom assessment and management where possible.
Table 1
| CKD N=63 | Haemodialysis N=111 | Home therapies N=49 | Transplant N=67 | |
| Median number of symptoms experienced* | 4 (IQR: 7) | 5 (IQR: 6) | 4 (IQR: 5) | 1 (IQR: 4) |
| 1st most common Symptom and % experiencing | Weakness 50.8% | Weakness 63.96% | Weakness 55.10% | Weakness 37.31% |
| 2nd most common Symptom and % experiencing | Poor Mobility 38.1% | Poor Mobility 57.66% | Poor Mobility 40.81% | Difficulty Sleeping 31.34% |
| 3rd most common Symptom and % experiencing | Difficulty Sleeping 38.1% | Difficulty Sleeping 43.24% | Difficulty Sleeping 40.81% | Feeling anxious & Shortness of Breath 20.9% |
*Questionnaire explored 17 symptoms in total