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Abstract: SA-PO847

A Tale of Two Neighborhoods: Association of Neighborhood-Level Social and Environmental Contexts with High CKD Prevalence

Session Information

Category: CKD (Non-Dialysis)

  • 2101 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Authors

  • Mohottige, Dinushika, Duke University School of Medicine, Durham, North Carolina, United States
  • Maxson, Pamela J., Duke University, Center for Community and Population Health Improvement, Durham, North Carolina, United States
  • Bhavsar, Nrupen Anjan, Duke University School of Medicine, Durham, North Carolina, United States
  • Lyn, Michelle J., Duke University, Durham, North Carolina, United States
  • Diamantidis, Clarissa Jonas, Duke University School of Medicine, Durham, North Carolina, United States
  • Boulware, L. Ebony, Duke University School of Medicine, Durham, North Carolina, United States
Background

Although CKD risk has been linked to neighborhood income, its association with other neighborhood contexts is less clear.

Methods

We estimated the 2017 prevalence of KDIGO CKD 3-5 among adults age 30 and older living in 153 Durham County census block groups (i.e. ‘neighborhoods’). Data were derived from the Durham Neighborhood Compass, a publicly available platform which integrates local electronic health record data with social and environmental data from 153 neighborhoods in Durham County, North Carolina-- a diverse US county of 295,373 residents. We characterized differences in neighborhood contexts reflecting social cohesion, economic stability, safety, transportation and the built environment among neighborhoods with ‘high’ CKD prevalence (above median county CKD prevalence among residents age 30-64 and age 65+) vs. ‘low’ CKD prevalence. In logistic regression models, we quantified the association of specific contexts with ‘high’ (vs. ‘low’) neighborhood CKD prevalence while adjusting for neighborhood median age and % black population.

Results

Among all 153 neighborhoods, the mean (SD) prevalence of CKD 3-5 was 2 (1.1)% and 11.7 (4.3)% among those age 30-64 and 65+, respectively. Nearly a quarter (22%) of neighborhoods (27,619 residents) had ‘high’ CKD prevalence. Contexts of ‘high’ and ‘low’ CKD prevalence neighborhoods varied substantially. After adjustment, neighborhoods with above median violent crimes, evictions, and impervious areas had greater odds of ‘high’ (vs. ‘low’) CKD prevalence; neighborhoods with above median household income and primary election participation had lower odds of ‘high’ (vs. ‘low’) CKD prevalence.

Conclusion

Durham neighborhoods with high and low CKD prevalence had substantially different social and environmental contexts. Further study of the influence of these factors on CKD risk is warranted.

Funding

  • NIDDK Support