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Kidney Week

Abstract: TH-PO1141

Pre-Transplant Cognitive Impairment Is Associated with Increased Rates of Early Post-Transplant Rehospitalization

Session Information

Category: Transplantation

  • 1902 Transplantation: Clinical

Authors

  • Gupta, Aditi, University of Kansas Medical Center, Kansas City, Kansas, United States
  • Montgomery, Neal, University of Kansas Medical Center, Kansas City, Kansas, United States
  • Bedros, Victor, University Of Kansas Medicar Center, Manhattan, Kansas, United States
  • Lesko, John, University of Kansas Medical Center, Kansas City, Kansas, United States
  • Thomas, Tashra S., University of Kansas Health System, Leawood, Kansas, United States
  • Chakraborty, Shweta, The University of Kansas Health System, Kansas City, Kansas, United States
  • Mahnken, Jonathan D., The University of Kansas Medical Center, Kansas City, Missouri, United States
  • Burns, Jeffrey M., University of Kansas School of Medicine, Kansas City, Kansas, United States
  • Cibrik, Diane Marie, University of Kansas Hospital, Parkville, Missouri, United States
Background

Cognitive impairment is common in patients with kidney disease and can affect patients understanding of transplant care and kidney transplant (KT) outcomes.

Methods

We conducted a single-center longitudinal cohort study to evaluate the association of pre-transplant Montreal cognitive assessment (MoCA) scores with length of hospitalization for KT and post-transplant rehospitalization rates. We used multiple regression for duration of hospitalization for KT and logistic regression for rehospitalization within 30 days.

Results

In total, 207 patients underwent MoCA testing before transplant and were included in the analysis. Patients with cognitive impairment were more likely to be older, black, and smokers (Table 1). The duration of hospitalization was independent of MoCA score, but associated with a history of coronary artery disease (β coeff=2.29, p= 0.002) and duration of dialysis before KT (β coeff=0.56, p<0.001). The odds of readmission within 30 days was higher with lower MoCA scores (Table 2).

Conclusion

Pre-KT cognitive impairment does not affect length of hospitalization for KT, but is associated with higher odds of 30-day rehospitalization after KT.

Table 1

Table 2

Funding

  • Other NIH Support