Abstract: SA-PO913
Correspondence of Ankle-Brachial Index and Doppler Ultrasound Findings in Patients with CKD
Session Information
- CKD: Clinical, Outcomes, Trials - III
November 09, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2102 CKD (Non-Dialysis): Clinical, Outcomes, and Trials
Authors
- Sharshir, Moh'd, Tulane School of Medicine, New Orleans, Louisiana, United States
- Atari, Mohammad, Tulane School of Medicine, New Orleans, Louisiana, United States
- Bai, Shuo, Tulane University, New Orleans, Louisiana, United States
- Bokhari, Syed Rizwan A., Tulane School of Medicine, New Orleans, Louisiana, United States
- Nakkar, Talal, Tulane School of Medicine, New Orleans, Louisiana, United States
- Erol, Halil K., Tulane School of Medicine, New Orleans, Louisiana, United States
- Chen, Jing, Tulane School of Medicine, New Orleans, Louisiana, United States
Background
Ankle-brachial index (ABI) is used to diagnose peripheral artery disease (PAD). ABI may be artificially high among patients with chronic kidney disease (CKD) due to increased arterial calcification and stiffness. It is not well studied how ABI and toe-brachial index (TBI) are correlated with more accurate diagnostic measures of doppler ultrasound in evaluating PAD in CKD.
Methods
We conducted retrospective chart review among pre-dialysis CKD patients in Tulane Hospital in New Orleans, Louisiana. Total of 251 were included in the study. De-identified demographic information, clinical measures, ABI, TBI, and doppler ultrasound findings were extracted into the study forms. The correlations of ABI, TBI, doppler waveforms, and peak systolic velocity (PSV) were analyzed. PSV is calculated as percentage change of measured PSV from normal value.
Results
Among patients with ABI ≤ 0.9, 73% had normal US waveform, 24% had biphasic waveform, and 3 % had monophasic waveform; 54% had TBI ≤ 0.7. Among those with ABI > 1.4, 77% had normal waveform, 23% had biphasic waveform, and 0% had monophasic waveform; 0% had TBI≤ 0.7. Among those with TBI ≤ 0.7, 50% had normal waveform, 43% had biphasic waveform, and 7% had monophasic waveform. In addition, ABI ≤ 0.9 or >1.4 and TBI ≤ 0.7 were poorly corelated with a ≥30%- <100% or ≥ 100% increase in PSV.
Conclusion
These data indicate that the ABI and TBI diagnostic criteria for PAD needs to be further evaluated in CKD. Larger study is warranted to confirm these study findings.