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Abstract: TH-PO302

Elderly Patients in Peritoneal Dialysis: Concerns Regarding Albumin Loss

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis


  • Gois, Jeison, Universidade de Sao Paulo, Sao Paulo, Brazil
  • Costa, Rebeca, Universidade de Sao Paulo, Sao Paulo, Brazil
  • Barbosa, Géssica Sabrine braga, Universidade de Sao Paulo, Sao Paulo, Brazil
  • Cordeiro, Lilian, Universidade de Sao Paulo, Sao Paulo, Brazil
  • Pereira, Benedito J., Universidade de Sao Paulo, Sao Paulo, Brazil
  • Abensur, Hugo, Universidade de Sao Paulo, Sao Paulo, Brazil
  • Moyses, Rosa M.A., Universidade de Sao Paulo, Sao Paulo, Brazil
  • Elias, Rosilene M., Universidade de Sao Paulo, Sao Paulo, Brazil

Albumin loss in peritoneal dialysis is associated with morbidity and mortality among patients on peritoneal dialysis (PD). Since elderly patients had a higher risk of protein-energy wasting, there has been a concern of further impairment of nutritional status in this population.


This is an observational prospective study that included patients >65 years (elderly group, N=18) compared to patients <65 years (younger group, N=73). Patients were followed for a median period of 21.8 months after PD initiation in a single center.


Patients >65years (50% diabetic, 78% men) started PD with a residual diuresis of 1.4± 0.5L, which did not differ from the young group (1.5± 0.7L); p=0.778. Elderly patients had lower serum creatinine (p=0.0001), serum phosphate (p=0.010), total protein (p=0.010), and higher bicarbonate (p=0.003), denoting impaired nutritional status. Serum 25(OH)-vitamin D at PD initiation was similar between groups (p=0.705). During follow-up, there was a slightly reduction of serum albumin in young patients (from 3.76±0.5 to 3.62±0.6mg/dl, p=0.0001), which did not reach statistical significance in the elderly population (from 3.67±0.4 to 3.57±0.4mg/dl, p=0.335), with a median change overtime of 0.14 and 0.10mg/dl in young and elderly patients, respectively (p=0.834). As expected, there was a weight increase over time, although not different comparing young and elderly patients (p=0.579). In addition, loss of residual renal function, and changes in hemoglobin, serum ferritin, iron saturation, β-2 microglobulin, and parathormone were similar between groups (all p>0.05).


Our findings suggest that there is no medical concern to avoid PD therapy in elderly patients with end-stage renal disease, at least in those who start therapy with no critical nutritional condition.