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Abstract: TH-PO093

Incidence, Associated Factors, and the Survival After 1-Year Follow-Up in Patients with Community-Acquired AKI Admitted to the Emergency Room

Session Information

Category: Acute Kidney Injury

  • 101 AKI: Epidemiology, Risk Factors, and Prevention

Authors

  • Argudo sanchez, Diego Fernando, Hospital General de Mexico, Mexico City, Distrito FEDERAL, Mexico
  • Perez-Navarro, L. Monserrat, Hospital General de Mexico, Mexico City, Distrito FEDERAL, Mexico
  • Merino, Maribel, Hospital General de Mexico, Mexico City, Distrito FEDERAL, Mexico
  • Valdez-Ortiz, Rafael, Hospital General de Mexico, Mexico City, Distrito FEDERAL, Mexico
Background

Community acquired acute kidney injury (AKI-CA)is defined in patients who, at the time of admission to the hospital, present criteria for acute kidney injury diagnosis. The acute kidney injury (AKI) is frequent complication among inpatients in the emergency room (ER). Our aims were to know the incidence, associated factors and the one-year survival of patients with AKI-CA.

Methods

Prospective cohort of admitted patients in the ER. The AKI was defined according to KDIGO 2012 criteria. The groups were compared using the Student's t-distribution or the X2 distribution, logistic regression was performed for OR and a Cox regression for HR and survival with IC 95% and p≤0.05.

Results

Eight hundred thirteen patients with an average age of 52.4±18 years were included. The 55% (443) were men. The incidence of AKI-CA was 55%, where 32.5% was due to AKI-1, 15% AKI-2, and 7.5% AKI-3. The associated factors with the develop of AKI-CA were hypertension (OR: 1.5, IC95% 1.1-2), liver failure (OR: 3.5, IC95% 1.8-6.3), chronic kidney disease (OR:3.82, IC95% 1.7-8.3), sepsis OR:3.48, IC95% 2.3-5.1), and surgical pathology (OR:2.55, IC95% 1.7-3.8). According to the state of AKI the inpatients days increased (AKI-1:10.7, AKI-2:12.8, AKI-3:14.2 days, p< 0.001). The risk of death during the inpatients days did not exhibit significant differences among the patients with and without AKI (p=0.23, Figure 1). However, the analysis after a one-year follow up showed a mortality of 64% in patients with AKI-CA versus 36% in patients that did not suffer it (p<0.001), with increased mortality risk (Figure 1b).

Conclusion

A high incidence of AKI at the time of admission and with an impact on survival over one year of follow-up.