Abstract: TH-PO1034
One Year of the State Registry of CKD in Aguascalientes Mexico: Have We Found a New Hotspot of CKD?
Session Information
- Glomerular Diseases: Epidemiology, Mechanisms, Complications, Outcomes
November 07, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Glomerular Diseases
- 1203 Glomerular Diseases: Clinical, Outcomes, and Trials
Author
- Arreola Guerra, Jose Manuel, Centenario Hospital Miguel Hidalgo, Aguascalientes, Mexico
Background
According to the Institute for Health Metrics and Evaluation, in Mexico the global burden attributed to chronic kidney disease (CKD) is one of the highest worldwide. Unfortunately the country don’t have any official registry. Since June 2018, the Health Council from Aguascalientes brought together the main health institutions that provide renal replacement therapy to start the state registry of CKD
Methods
Describe the results of the first year of data collection of the Aguascalientes CKD registry
Results
Until May 2019, 2,574 patients have been registered, of whom 93 have died and 321 are transplanted. The estimated prevalence is 1,526 pmp (n= 2,160). The most common causes are CKD are: of unknown origin (n= 981, 45.4%), Diabetes Mellitus (n=681, 31.5%), Systemic Arterial Hypertension (n= 326, 15%). The most prevalent modality of renal substitution was hemodialysis (n= 1,365, 63.1%). 59% are men (n= 1,274). The average age of the patients included was 46.5 years, with a bimodal distribution. The first group between 20 and 39 yo (n= 1,107, 51.2%) and the second between 50 and 69 yo (n= 843, 39%). Since January 2012, 389 kidney biopsies have been performed in the state. The main diagnosis was focal and segmental glomerulosclerosis(FSGS) (n= 128, 32.9%), followed by lupus neph (n= 55, 14.1%), IgA neph (n= 48, 12.3%), minimal changes dis (n= 45, 11.5) and membranous neph (n= 22, 5.6%)
Conclusion
In Aguascalientes Mexico, we have a high prevalence of CKD.The main cause is of unknown origin. The main affected group are young adults between 20 and 40 y and the most frequent glomeulopathy in this group was FSGS. At this moment a study of screening of CKD in adolescents in the state is being developed which is expected to contribute to the study of the causes of CKD in our population
Characteristics by age groups
| Variable | Group 1 (20 to 39 yo) n= 1,107 | Group 2 (50 – 69 a) n= 843 | p value |
| Male sex, n(%) | 726 (65.5) | 486 (57.6) | <0.01 |
| CKDuknown origin, n (%) | 574 (51.8) | 225 (26.6) | <0.01 |
| Diabetes, n(%) | 83 (7.5) | 352 (41.7) | <0.01 |
| HTN, n(%) | 109 (9.8) | 136 (16.1) | <0.01 |
| Renal Biopsies | N= 136 | N=44 | p value |
| FSGS, n(%) | 60 (44.1) | 12 (27.2) | 0.04 |
| Lupus N, n(%) | 19 (13.9) | 8 (18) | 0.45 |
| IgA N, n(%) | 17 (12.5) | 8 (18) | 0.40 |
FSGS: Focal segmental glomerulosclerosis, HTN: Systemic Hypertension, N: Nephritis