ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on Twitter

Kidney Week

Abstract: INFO15-FR

Diabetic Kidney Disease Cohort in the Million Veteran Program (MVP)

Session Information

  • Informational Posters - II
    November 08, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Diabetic Kidney Disease

Authors

  • Ramos, Everly faith P., Vanderbilt University Medical Center, Nashville, Tennessee, United States
  • Fried, Linda F., VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States
  • O'Donnell, Christopher Joseph, Boston Veterans Administration, Boston, Massachusetts, United States
  • Phillips, Lawrence S., Atlanta VA Health Care System, Decatur, Georgia, United States
  • Wilson, Peter W., Emory University, Atlanta, Georgia, United States
  • Hung, Adriana, VA & Vanderbilt University, Nashville, Tennessee, United States
Description

The MVP was established by the VA Research to advance precision and genomic medicine. Data from health records, surveys and blood samples are stored securely in independent databases. The VA is a closed health care system that provides a wealth of phenotypic information for their patients that can be followed longitudinally over time. The information consists of demographics, diagnosis and procedure codes, laboratory values, vital signs, pharmacy files, pathology and hospitalizations. Among the 650,749 veterans that has been enrolled since 2011, 202,482 (31%) have type 2 diabetes mellitus. At baseline, while 99% had serum creatinine measurements, 22% were lacking albuminuria measurements and were not included in our cohort. We estimated eGFR using the CKD-EPI equation. These data allowed us to create a well-phenotyped DKD cohort that contains relevant data on diabetic-related complications and co-morbid conditions (see Table 1). The MVP contains the largest phenotypic DKD cohort linked to genotypic data in the world.

Table 1. Characteristics of patients with Diabetic Kidney Disease in the MVP.

Funding

  • VA Research through the Million Veteran Program.