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Abstract: PO1217

Low-Sodium Home-Delivered Meals Reduce Thirst and Xerostomia in Patients on Hemodialysis

Session Information

Category: Dialysis

  • 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Ashrafi, Sadia anjum, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States
  • Perez, Luis M., University of Illinois at Urbana-Champaign, Urbana, Illinois, United States
  • Wilund, Kenneth Robert, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States
Background

Hemodialysis (HD) patients are often advised to restrict dietary sodium and fluid. Thirst and xerostomia contribute to non-adherence with fluid restricted diets resulting in fluid retention and chronic volume overload. Dietary sodium restriction may reduce thirst and xerostomia, which may, in turn, reduce fluid intake and retention. The purpose of the study was to determine if 4-weeks of low-sodium home-delivered meals reduces HD patient’s subjective thirst and xerostomia.

Methods

Twelve HD patients had 3 low sodium meals/day (Mom Meals, Inc) delivered to their homes for 4 weeks. On average they were on 17 medicines among which 7 (Mean) had prior evidence to induce xerostomia. Subjective thirst and xerostomia were measured at three time points: baseline (BL), after 4 weeks of low sodium meals (INT), and 4 weeks post-meals (POST[SAA1] ). Thirst was measured using the dialysis thirst inventory scale (DTI) that had 7 domains describing thirst, and numerical rating scale for thirst (NRS-T) while xerostomia was measured with a numerical rating scale for dry mouth (NRS-X) and the xerostomia inventory scale (XI) that had 11 domains describing dry mouth symptoms.

Results

Participant's mean thirst during the day, thirst after HD, thirst’s influence on social life, dry mouth feeling, total XI, NRS-T, NRS-X scores were significantly lower during INT compared to BL (Mean±SD scores from BL to INT: 3.1±1 to 2±1; 3.5±1 to 2.2±1; 2±2 to 1.3±0.9; 2.9±1 to 1.9±0.8 on the scale of 1-5; 28.5±12 to 19.3± 9 on the scale of 1-55; 6±3 to 2.8±2 and 5.5±3 to 3.1±2 on the scale of 0-10, respectfully; p<0.05). The score of thirst’s influence on social life and NRS-T were significantly higher in POST compared to INT (Mean±SD scores from INT to POST: 1.3±0.9 to 1.7±1; 2.8±2 to 4.5±2.6; p<0.05). NRS-T is significantly lower in POST compared to BL (Mean±SD scores from BL to POST: 6±3 to 4.5±2.6; p<0.05)

Conclusion

Multiple domains of subjective thirst and xerostomia decreased after 4 weeks of home-delivered low sodium meal consumption but generally returned close to baseline 4 weeks after cessation of the meal delivery. The feasibility and efficacy of long-term meal provision for reducing thirst, xerostomia, and chronic volume overload need to be further evaluated in future studies.