ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on Twitter

Kidney Week

Abstract: PO1341

Estimated Upper-Body Blood Flow and Central-Venous Oxygen Saturation Before and After Percutaneous Transluminal Angioplasty in Newly Created Vascular Access

Session Information

  • Vascular Access
    October 22, 2020 | Location: On-Demand
    Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

  • 704 Dialysis: Vascular Access

Authors

  • Rosales, Laura, Renal Research Institute, New York, New York, United States
  • Zhang, Hanjie, Renal Research Institute, New York, New York, United States
  • Mateo, Marilou, Renal Research Institute, New York, New York, United States
  • Chan, Brenda Kim, Renal Research Institute, New York, New York, United States
  • Johnson, Seth, Renal Research Institute, New York, New York, United States
  • Thijssen, Stephan, Renal Research Institute, New York, New York, United States
  • Kotanko, Peter, Renal Research Institute, New York, New York, United States
Background

Arterio-venous fistula (AVF) is the most effective vascular access in hemodialysis (HD) patients and, assessing AVF maturation is critical to initiate its timely use. Previously we have demonstrated that central-venous oxygen saturation (ScvO2) and estimated upper-body blood flow (eUBBF) increase during AVF maturation. We assessed ScvO2 and eUBBF before and after percutaneous transluminal angioplasty (PTA).

Methods

We studied HD patients from an ongoing AVF quality improvement project. ScvO2 and hematocrit were measured with Crit-Line (FMC, Waltham, MA) between minutes 5 and 20 into HD. eUBBF was computed and described previously (Rosales, Blood Purif, 2019). Five out of 19 patients underwent PTA during AVF maturation and subsequent successful cannulation.

Results

Three of five patients (mean age 71±11) were males two were incident patients. Four interventions were due to venous stenosis and one was due to arterial anastomosis stenosis. Two patients underwent PTA 2.2 ± 0.3 weeks after AVF creation and the remaining 3 patients within 11.2 ± 4 weeks. Following PTA ScvO2 increased in all, except in patient #1, eUBBF increased in every patient (Table 1).

Conclusion

Our preliminary results indicate that ScvO2 and eUBBF provide functional information that can be obtained non-invasively. These point-of-care bio-signals reflect hemodynamic cardiovascular adaptation following successful PTA. Future studies are warranted if knowledge of ScvO2 and of eUBBF shorten catheter residence time.