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Kidney Week

Abstract: PO2058

Effect of Exercise on Quality of Life and Functional Capacity in Patients with CKD

Session Information

Category: Health Maintenance, Nutrition, and Metabolism

  • 1300 Health Maintenance, Nutrition, and Metabolism

Authors

  • Bandi, Varun kumar, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences & RF, Gannavaram, Andhra Pradesh, India
  • Kolli, Haneesha, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Nimmagadda, Sreelakshmi, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Komatla, Sandhya, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
Background

Chronic kidney disease patients have lower activity levels when compared to normal population, compounded by sedentary lifestyle and is associated with increased mortality, which might reduce with exercise

Methods

Patients with chronic kidney disease were evaluated for 12 weeks of supervised exercise program. The subjects were divided into 2 groups: Group I (CKD stage 3-5) and Group II (CKD on maintenance hemodialysis). Serum hemoglobin (Hb), calcium (Ca), phosphorous (Pi), and albumin (Alb) were done at baseline and at 12 weeks. Symptom burden was assessed using Functional Assessment of Chronic Illness Therapy-Fatigue Scale (FACIT-F) and Leicester Uremic Symptom (LUS) Scale, Quality of life using SF-36 questionnaire, functional capacity using Duke Activity Status Index, Physical activity using Godin-Shephard Leisure time Exercise Questionnaire and Nutritional status using modified Subjective Global Assessment at baseline and at 12 weeks. Subjects in Group I were advised aerobic and resistance exercises at home, with once in 3 weeks hospital visit. Subjects in Group II underwent aerobic and resistance exercise in the pre-dialytic and intra-dialytic period during every dialysis visit

Results

Group I included 28 patients, while group II had 30 patients. At baseline, Hb and Albumin were significantly different between groups, while other parameters and scores were similar. At baseline, SF-36 and FACIT-F significantly correlated positively with Hb, Alb, Ca and Pi, while SGA correlated significantly with Alb, Ca & Pi. At end of study, in group I there was a non- significant increase in SF-36 (p=0.41), and DUKES (p=0.17), with a non-significant decrease in LUS (p=0.36), FACIT-F (p=0.83) and SGA (p=0.1136), while in group II there was a significant increase in SF-36 (p<0.001), with non-significant increase in Dukes (p=0.75), and a significant decrease in LUSS (p<0.001), SGA (p<0.05) and FACIT-F (p<0.001)

Conclusion

Exercise increased the quality of life and decreased symptom burden but there was an increase in fatigue perception in patients on dialysis. However, LUSS reduced with reduced FACIT-F which could mean decrease in symptom burden but persistence of fatigue. In patients not on dialysis there was no significant increase in quality of life or decrease in symptom burden.