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ASN / Education & Meetings / Kidney Week /

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Abstract: PO0055

COVID-19 Outcomes in Hospitalized Patients with CKD

Session Information

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Suresh, Varsha V., University of Central Florida, Orlando, Florida, United States
  • Khine, Kay Thi, University of Central Florida, Orlando, Florida, United States
  • Borgan, Saif M., Cleveland Clinic, Cleveland, Ohio, United States
  • Castro, Francheska, University of Central Florida, Orlando, Florida, United States
  • Patel, Hiren, Saint Louis University, Saint Louis, Missouri, United States
  • Asmar, Abdo, University of Central Florida, Orlando, Florida, United States
Background

Current research revolving around Coronavirus Disease 2019 (COVID-19) has identified that patients with co-morbid illnesses are at risk for worse outcomes.

Methods

This is a retrospective study comprising an observational dataset of 149 hospitals that included hospitalized patients (n=9366) aged 18 and above with a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Polymerase Chain Reaction (PCR) positive result between January 1st, 2020 and May 29th, 2020. Main outcomes and measures included hospital length of stay, Intensive Care Unit (ICU) admission, ventilator dependency, development of Acute Kidney Injury (AKI) and in-hospital death. Baseline patient characteristics were recorded, including demographic variables and comorbidities.

Results

A total of 9,366 patients were included in the analysis, of which 4765 (50.8%) were males, with mean age of 55.4 years (SD=18.6). Patients with CKD (n=1092, 11.7%) had a significantly higher length of hospital stay (Mean of 10.5 vs 4.9 days), ICU admission rates (23.3% vs 13.0%), ventilator dependency (24.5% vs 9.3%), AKI (6.2% vs 1.9%) and in-hospital death (20.5% vs 5.9%). In a multivariable logistic regression model, in-hospital death was independently related to presence of CKD.

Conclusion

This study confirms the independent association between a personal history of CKD and poor outcomes among hospitalized patients with COVID19, including in-hospital death.