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Abstract: PO0989

Multifrequency Bioimpedance Is a Useful Adjunct to Control Fluid Overload in PD Patients

Session Information

  • Peritoneal Dialysis
    November 04, 2021 | Location: On-Demand, Virtual Only
    Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

  • 702 Dialysis: Home Dialysis and Peritoneal Dialysis

Authors

  • Li, Szu-Yuan, Taipei Veterans General Hospital, Taipei, Taiwan
  • Chuang, Chiao-Lin, Taipei Veterans General Hospital, Taipei, Taiwan
  • Chen, Jinn-Yang, Taipei Veterans General Hospital, Taipei, Taiwan

Group or Team Name

  • Taipei Veterans General Hospital PD team
Background

Fluid overload is a well recognized phenomenon in many peritoneal dialysis (PD) patients, but a balance between reduction of dry weight and preservation of residual renal function (RRF) is mandatory. We hypothesize that, to achieve an ideal dry weight, adjustment by multi-frequency bioimpedance (MF-BIA) guide offers less adverse effect on residual renal function than that by clinical judgment alone.

Methods

The hydration status of various body compartments were measured using a MF-BIA device (Inbody 720, Biospace). The normalized hydration score was defined as extracellular water (ECW)/total body water (TBW). All patients were evaluated monthly for 6 months. The dry weight of study group was adjusted according to MF-BIA to avoid dehydration, and the dry weight of control group was determined clinically. Ambulatory blood pressure, anti-hypertension medication dosage, serum biochemical parameters, and RRF were recorded monthly. IL-6 and hs-CRP will be checked before and after the study.

Results

93 stable PD patients (48 in study and 45 in control group) completed the study. ECW/TBW ratio was higher in PD patients than sex- and age- matched healthy subjects. (Figure 1). In PD patient, the ratio of ECW/TBW was positive correlated to age (r = 0.534), peritoneal D/P ratio (r = 0.518), systolic BP (r = 0.526) and negative correlated to urine volume (r = -0.526), serum albumin (r = -0.658).
After 6 months intervention, study group decreased 1.2 kg and control group gained 0.2 kg. The study group had a better systolic and diastolic BP control and a higher serum albumin (3.75 ± 0.61 vs 3.48 ± 0.68 g/dl , p = 0.047). The RRF has no difference between two groups.

Conclusion

Our results showed that correction of fluid overload would improve blood pressure control. Being an objective tool to assess hydration status of various body compartments, MF-BIA is a useful adjunct to correct fluid overload without the loss of RRF in our short-term study.