Abstract: TH-PO713
Dialysis Modality-Related Disparities in Sudden Cardiac Death: Hemodialysis vs. Peritoneal Dialysis
Session Information
- Hypertension and CVD: Epidemiology, Risk Factors
November 07, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Hypertension and CVD
- 1401 Hypertension and CVD: Epidemiology, Risk Factors, and Prevention
Authors
- Jung, Hee-Yeon, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
- Choi, Ji-Young, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
- Cho, Jang-Hee, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
- Park, Sun-Hee, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
- Kim, Chan-Duck, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
- Kim, Yong-Lim, Kyungpook National University Hospital, Daegu, Korea (the Republic of)
Background
Patients require risk stratification and preventive strategies for sudden cardiac death (SCD) according to dialysis modality, as the process of dialysis itself is a risk factor for SCD. This study aimed to compare the risk of SCD in patients receiving hemodialysis (HD) or peritoneal dialysis (PD).
Methods
Patients on HD or PD were included from the end-stage renal disease registry of the Korean Society of Nephrology between 1985 and 2017. The incidence and associated factors of SCD were analyzed according to dialysis modality.
Results
Among 132,083 patients, 34,632 (35.5%) patients died during 94.8 ± 73.6 months of follow-up. In patients on HD and PD (P < 0.001), 22.2 and 19.6% of total death were SCDs. HD was independently associated with SCD even after adjusting age and significant comorbidities (adjusted odds ratio [OR] 1.14, 95% confidence interval [CI] 1.07–1.22, P < 0.001). The presence of hypertension (adjusted OR 1.14, CI 1.08–1.22, P < 0.001) and congestive heart failure (adjusted OR 1.26, CI 1.15–1.39, P < 0.001) and age < 65 (adjusted OR 1.06, CI 1.00–1.13, P = 0.041) were independent risk factors for SCD in patients on HD but not in those on PD. Diabetes was significantly associated with SCD regardless of dialysis modality.
Conclusion
Korean patients on HD compared to PD faced a higher risk of SCD attributable to cardiac comorbidities.