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Abstract: TH-PO301

The Value of Geriatric Nutritional Risk Index in the Prognosis of Patients with Maintenance Peritoneal Dialysis

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis

Authors

  • Li, Afang, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
  • Dou, Yanna, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
  • Xiao, Jing, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
  • Zhao, Zhanzheng, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Background

Geriatric Nutritional Risk Index (GNRI) has been reported related to the prognosis and medical expenses of dialysis patients, but there are few related studies about Chinese patients, especially in terms of peritoneal dialysis (PD). The aim of this study was to explore the value of the GNRI in patients with end-stage renal disease at beginning of PD treatment.

Methods

Retrospectively analyze the medical records of patients undergoing peritoneal dialysis catheterization and starting peritoneal dialysis in the First Affiliated Hospital of Zhengzhou University from January 1, 2013 to December 30, 2018. Collect basic data and biochemical indicators of these patients in the first hospitalization for peritoneal dialysis catheterization. Follow-up these patients until March 1, 2019, and using death or turning to hemodialysis as endpoints, divide the patients into two groups according to the GNRI cutoff based on the ROC curve. Compare the clinical data and laboratory test results between the two groups, Kaplan-Meier analysis was used to observe the difference during follow-up,and the relevant factors affecting effect of peritoneal dialysis were estimated by binary logistic regression.

Results

The GNRI cut-off value was determined to be 90.5 according to the ROC curve, and the drop-out rate of GNRI≤90.5 group was significantly higher than the GNRI>90.5 group(35.9% VS 21.6%,P=0.003), and Kaplan-Meier survival curves showed a higher rate of peritoneal dialysis in the higher GNRI group during follow-up (P=0.021). Logistic univariate regression showed that male, GNRI and Alb were protective factors for PD patients, and after multi-factor correction, male and GNRI were also shown to be protective factors for PD patients.

Conclusion

The baseline GNRI can be used as a prognostic indicator for peritoneal dialysis patients.

Funding

  • Government Support - Non-U.S.