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Abstract: FR-PO503

Influence of Season and Climatic Conditions on Peritoneal Dialysis-Associated Peritonitis in a Subtropical Monsoon Climate Region of China

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis

Author

  • Zhang, Hao, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Background

Peritoneal infections are a common complication in patients undergoing peritoneal dialysis (PD) and are frequently the cause of the failure of the technique. Knowing the factors that can lead to theirappearance helps to establish preventative measures.The aim of this research is to understand the influence of season, temperature and humidity on peritoneal dialysis-associated peritonitis in the subtropical monsoon climate region(Hunan provence) in China.

Methods

A retrospective observational study of all peritoneal dialysis-associated peritonitis that occurred in our PD center over a period of 9 years (2009-2017).Our PD center is located in hunan province, China which has the subtropical monsoon humid climate .Demographic data of patients, biochemical indicators at the time of onset, culture results of dialysate fluid, and data of the humidity and temperature of the months from 2009 to 2017 in hunan province were collected.

Results

There were 448 cases of peritonitis(0.17episodes/patient/year) in 885 patients (47±13 years, 56.4% males,8.7% diabetics, 50.2±19
months on technique).There was significant seasonal variation in the rate of overall peritonitis and gram-negative bacteria peritonitis , with peak incidence in June. When comparing the incidence of peritonitis in different seasons, we found the incidence rates of overall peritonitis and gram-negative bacteria peritonitis were the highest in summer, respectively(p<0.05).But we did not find this variation upon analysing the incidence rates of peritonitis caused by gram-positive bacteria.There was significant correlation between monthly peritonitis rate and the average monthly temperature (r=0.258, p=0.018).There was significant correlation between monthly gram-negative bacteria peritonitis rate and the average monthly temperature (r= 0.278,p=0.010) either.But we did not find correlation between the incidence rates of peritonitis and average humidity.

Conclusion

The rates of overall peritonitisand and gram-negative bacteria peritonitisperitonitis are the highest in summer.The higher the temperature, the higher the risk of overall peritonitis and especially of gram-negative bacteria.