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Abstract: TH-PO1021

Application of International Tool for Risk Prediction in IgA Nephropathy in Mexican Patients

Session Information

Category: Glomerular Diseases

  • 1203 Glomerular Diseases: Clinical, Outcomes, and Trials

Authors

  • Rojas, Flor Elena, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
  • Diaz villar, Jineth Leidy, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
  • Perez, Myriam K., Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
  • Rosero, Ivan, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
  • Cordoba hurtado, Angela Maria, Universidad Nacional Autonoma de Mexico, Ciudad de Mexico, Mexico
  • Soto, Virgilia, INC Ignacio Chavez, Mexico City, Mexico
  • Valdez-Ortiz, Rafael, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
  • Perez-Navarro, L. Monserrat, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico
Background

IgA nephropathy is one of the main causes for chronic kidney disease with a progressive deterioration of kidney function with a 10-year risk for end stage kidney disease ranging from 5-60%. Risk stratification is important for immunosuppressive therapy selection so a risk score was developed called international score tool for risk prediction in IgA nephropathy. The aim is determine the strength of association between the international score tool for risk prediction in IgA nephropathy and the lowering of the glomerular filtration rate at 6 months in Mexican patients with IgA nephropathy.

Methods

The study is a retrospective cohort with descriptive statistics, the international score for risk prediction in IgA nephropathy at the Hospital General de Mexico; a Pearson`s correlation test was performed with a significative p value <0.05 and IC95%.

Results

Twenty patients were included, mean age 35.2± 14.06 years, 65% (13) were male, glomerular filtration rate(GFR) at biopsy was 72.93± 40.67 ml/min/1.73 m2 CKD-EPI, GFR at 6 months post-biopsy 71.42 ± 36.05 ml/min/1.73m2 CKD-EPI. The correlation between the risk for lowering GFR by 50% at 6 months presented a strong correlation with a statistical significance (Figure 1).

Conclusion

The international score for risk prediction in IgA nephropathy can be used in Mexican patients.