Abstract: SA-PO963
Impact of Renal Replacement Therapies over Quality of Life of ESRD Patients
Session Information
- Peritoneal Dialysis: Inflammation, Peritoneal Transport
November 09, 2019 | Location: Exhibit Hall, Walter E. Washington Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 703 Dialysis: Peritoneal Dialysis
Authors
- Garcia, Araly, Instituto Nacional de Cardiologia, Mexico City, COYOACAN, Mexico
- Moguel, Bernardo, Instituto Nacional de Cardiologia, Mexico City, COYOACAN, Mexico
- Leal, Gabriela, Instituto Nacional de Cardiologia, Mexico City, COYOACAN, Mexico
Background
Renal transplant is generally considered as the ideal renal replacement therapy (RRT). Nonetheless, at the moment, hemodialysis and peritoneal dialysis remain as the main alternative treatment options for patients with end stage renal disease (ESRD). The negative impact of ESRD on the quality of life (QoL) has already been well described, and improvement of QoL could actually be translated into lower mortality.
Methods
Transversal, cohort, observational study, evaluating ESRD patients subjected to renal transplant (RT) , undergoing hemodiafiltration (HDF) or automated peritoneal dialysis (APD). QoL was assessed using the Kidney Disease Quality of Life Questionnaire (KDQOL-SF), as well as Becks inventories for anxiety and depression. Additional factors like dialysis quality, body composition, and muscle strength were also assessed.
Results
82 patients met the inclusion criteria: 32 RT patients, 26 on APD and 24 on HDF. 43% of them were in the age range between 31- 50 years. Lower phase angles and muscular strengths were measured in the HDF and APD groups when compared to RT patients (p=0.005) (p=0.0003). As for QoL, RT patients obtained better scores when compared to the other groups, however, statistically significant differences were only observed in five of the categories, which ultimately emphasized the importance of disease burden (p=0.0006 ) and effects of disease (p=0.0001). The HDF group had a slight tendency towards better QoL results than the APD group, without reaching statistical significance. Hydration status measured with bioelectrical impedance analysis revealed greater levels of overhydration in the HDF group, as expected, since measurement was performed pre HDF treatment (p=0.14). Higher levels of anxiety and depression were observed in the HDF group.
Conclusion
QoL of RT patients is superior to that of patients remaining on dialysis, yet on most of the categories assessed in the KDQOL-SF, no statistical significance was observed, suggesting QoL is acceptable, or even satisfactory, in patients on HDF and APD. As for these two dialysis modalities, there was no significant difference of QoL in our study group.