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Abstract: FR-PO1114

Comparing Infectious Diagnoses in ESKD Before and After the COVID Era

Session Information

  • COVID-19 - II
    November 03, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Manadan, Jay, Rush Nephrology, Chicago, Illinois, United States
  • Manadan, Neil, Rush Nephrology, Chicago, Illinois, United States
  • Patel, Nilam, Rush Nephrology, Chicago, Illinois, United States
  • Whittier, William Luke, Rush Nephrology, Chicago, Illinois, United States
Background

Undoubtedly, the 2020 worldwide COVID-19 pandemic had a major impact on healthcare. This study aims to compare infections among inpatients with end stage kidney disease (ESKD) before and after the onset of the pandemic in the USA.

Methods

All adult hospitalizations from the 2016-2020 National Inpatient Sample (NIS) database with a principal diagnosis of infection and a secondary diagnosis of ESKD were analyzed. We compared data between the pre-COVID era (2016-2019) with those from the COVID era (2020).

Results

990,550 hospitalizations between 2016-2020 had both an infection and ESKD. Of those, 752,640 were from the pre-COVID era and 237,910 were from the COVID era (figure 1). Those from the COVID era had less females, higher inpatient charges, and higher adjusted in-hospital mortality (14.4% vs 10.2%; p<0.001) (figure 1). In 2020, COVID-19 became the second most frequent infection seen in ESKD inpatients (figure 2). Various types of sepsis remained frequent in both groups, along with pneumonia, line infection, peritoneal dialysis catheter infection, and urinary tract infection.

Conclusion

ESKD patients with an infection experienced a higher adjusted in-hospital mortality in 2020. COVID became the second most common infection in ESKD patients in 2020. Nine of the top ten infections remained identical between the groups. Sepsis remained the predominant infection in the post-COVID era. This information should alert nephrologists to the frequency of COVID in ESKD inpatients.

Figure 1

Figure 2