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Abstract: TH-PO1088

Perceptions About Influenza and COVID-19 Vaccines Among People with CKD: CRIC Study

Session Information

  • COVID-19 - I
    November 02, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)


  • Ishigami, Junichi, Johns Hopkins University, Baltimore, Maryland, United States
  • Jaar, Bernard G., Johns Hopkins University, Baltimore, Maryland, United States
  • Lash, James P., University of Illinois Chicago, Chicago, Illinois, United States
  • Chen, Jing, Tulane University, New Orleans, Louisiana, United States
  • Appel, Lawrence J., Johns Hopkins University, Baltimore, Maryland, United States
  • Crews, Deidra C., Johns Hopkins University, Baltimore, Maryland, United States
  • Riekert, Kristin, Johns Hopkins University, Baltimore, Maryland, United States
  • Dowdy, David W., Johns Hopkins University, Baltimore, Maryland, United States
  • Matsushita, Kunihiro, Johns Hopkins University, Baltimore, Maryland, United States

Vaccine uptake in people with CKD is suboptimal. Understanding reasons for not getting vaccinated (“non-vaccination”) could inform programs seeking to address these concerns.


In a subset of Chronic Renal Insufficiency Cohort (CRIC) Study participants, we administered a survey on perceptions about influenza and COVID-19 vaccines. Survey development followed the Health Belief Model, including themes of perceived risk, perceived benefits and harms, and cues to action. Response was based on a 5-level Likert scale (strongly agree, agree, neutral, disagree, strongly disagree). The odds of agreeing to each statement in the questionnaire (strongly agree/agree vs. others) were compared between those who did and did not have non-vaccination status, defined as never having received either an influenza vaccine in the last 5 years or a COVID-19 vaccine at any point preceding the survey.


Between July 2022 and March 2023, 199 participants completed the survey (age 71 years, 42% female, 45% Black race, mean eGFR 50 ml/min/1.73m2); 24 (12%) and 35 (18%) had influenza and COVID-19 non-vaccination status. For both vaccines, agreeing that benefits are exaggerated, that people are lied to about the risks of vaccines, and that vaccines cause side effects were associated with higher odds of non-vaccination; whereas agreeing that vaccines prevent people from becoming seriously ill was associated with lower odds of non-vaccination (Figure). Agreeing that the vaccine causes people to get COVID-19, and that people who had influenza do not need the influenza vaccine, were associated with their non-vaccination status.


Among people with CKD, negative perceptions about vaccine safety and benefits were associated with non-vaccination status. Effectively communicating accurate information tailored by vaccine type may be essential to improve vaccination uptake in people with CKD.


  • NIDDK Support