ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

Abstract: TH-PO581

Inpatient and Outpatient Service Review of a Greek Reference Centre for Glomerular Diseases

Session Information

Category: Glomerular Diseases

  • 1402 Glomerular Diseases: Clinical, Outcomes, and Trials

Authors

  • Chalkia, Aglaia, Nephrology Department, Hippokration General Hospital, Athens, Greece
  • Koutsianas, Christos, 2nd Department of Medicine and Laboratory, Clinical Immunology - Rheumatology Unit, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece
  • Giannou, Panagiota E., Nephrology Department, Hippokration General Hospital, Athens, Greece
  • Tsalapaki, Christina, 2nd Department of Medicine and Laboratory, Clinical Immunology - Rheumatology Unit, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece
  • Mpora, Margarita, Nephrology Department, Hippokration General Hospital, Athens, Greece
  • Gakiopoulou, Harikleia, 1st Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
  • Tsioufis, Konstantinos, 1st Department of Cardiology, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece
  • Vassilopoulos, Dimitrios, 2nd Department of Medicine and Laboratory, Clinical Immunology - Rheumatology Unit, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece
  • Petras, Dimitrios I., Nephrology Department, Hippokration General Hospital, Athens, Greece
Background

The glomerulonephritis (GN) is a rare and complicated disease with high demand of hospital resources while the chronic kidney disease and end-stage renal disease present increased prevalence in these patients.

Methods

We retrospectively assessed the inpatient and outpatient service for patients with GN, who have been followed-up at a Greek reference centre for GN, during the pre-Covid-19 period 2018-2020.

Results

267 patients (median age 65±23 years) included. All patients underwent a kidney biopsy by the nephrologist without complications. ANCA associated GN (18%), Focal Segmental Glomerulosclerosis/Minimal Change Disease (17.5%), IgA nephropathy (17%), Membranous Nephropathy (12.6%), Lupus Nephritis (5%), Membranoproliferative GN (3%), Fibrillary GN (3%), Monoclonal Gammopathy of Renal Significance (3.3%) and IgG4-related disease (2%.) were encompassed. We reported median 75 new patients per year. Regarding the inpatient service, we observed an increasing trend to the hospitalizations during this period (274, 452, 461 hospitalizations in 2018, 2019, 2020 respectively). The AAV was the most common disease of hospitalizations through this period (53% in 2018, 33% in 2019, 39% in 2020), whereas the second most common was the FSGS/MCD (28% in 2018, 13% in 2019, 23.8% in 2020). The outpatient’s service review also revealed an increasing number of visits per person per year (279, 456 and 464 total visits in 2018, 2019 and 2020 respectively). The disease with the highest number of visits per person was reported the AAV (median 3.25 visits per patient per year). All the patients treated in collaboration with a multidisciplinary team, consisting of nephrologist, rheumatologist, cardiologist, and pathologist. Finally, we reported complete response at 76% of the patients and in terms of renal improvement, 46% presented eGFR≥60ml/min/1.73m2, 45% eGFR<60ml/min/1.73m2 and only 9% progressed to ESRD after the first year of treatment.

Conclusion

The patients with GN present an increased need for hospitalization and regular outpatient visits. In addition to the medical treatment, the favourable outcome depends on a well-organized inpatient and outpatient service provided by a multidisciplinary team.