ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005


The Latest on X

Kidney Week

Please note that you are viewing an archived section from 2023 and some content may be unavailable. To unlock all content for 2023, please visit the archives.

Abstract: SA-OR31

CKD Among Childbearing Age Women in the United States: NHANES 1999-2018

Session Information

Category: Women's Health and Kidney Diseases

  • 2200 Women's Health and Kidney Diseases


  • Zheng, Zihe, Brigham and Women's Hospital, Boston, Massachusetts, United States
  • Singh, Ajay K., Brigham and Women's Hospital, Boston, Massachusetts, United States
  • Farag, Youssef MK, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States

Previous studies reported 3% and up to 6% prevalence of CKD among pregnant women and women of childbearing age in high income countries, respectively. However, the prevalence and severity of CKD among women of childbearing age (20-49) in the US has not been well characterized. We aimed to examine this epidemiology evidence gap in a representative sample of the US adult population.


We analyzed data from the National Health and Nutrition Examination Survey (NHANES), 1999-2018. The definition of childbearing age for women was derived from the CDC vital and health statistics report. We used KDIGO guidelines to define CKD and the prognosis risk categories. We examined common kidney risk factors in the age group between 20 to 49, including eGFR, albuminuria, blood pressure, HbA1c, glucose, hemoglobin, BMI, and lipids. We used Poisson regression to estimate the CKD prevalence ratio comparing women to men in this age group.


The weighted period prevalence of CKD among childbearing age women in the US was 7.51%, while the prevalence of CKD among men in the same age group was 5.08%. Non-Hispanic black and Hispanic women of childbearing age had higher prevalence of CKD (9-10%). Fig 1 shows that more than 1 in 5 CKD patients with moderately increased KDIGO risk and more than 1 in 14 CKD patients with high/very high KDIGO risk were women of childbearing age. The percentage of Hispanics was higher among childbearing age females (20.2%) compared to females≥ age 50 (8.4%) in CKD patients. After adjusting for race/ethnicity and age, female gender was independently associated with 47% increased prevalence for CKD in the childbearing age group (PR=1.47, 95% CI 1.32, 1.63), yet female CKD patients showed largely more favorable profiles of common kidney risk factors compared to their male counterparts.


Our study highlighted that women of childbearing age had disproportionally higher prevalence of CKD in the US, especially among Hispanic women, than previously reported. Our findings quantify disparities and highlight the need and gaps in kidney/reproductive health among one of the most vulnerable populations in CKD patients.