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Kidney Week

Abstract: TH-PO592

A New Mexico-Based Kidney Biopsy Registry Data Analysis

Session Information

Category: Glomerular Diseases

  • 1402 Glomerular Diseases: Clinical, Outcomes, and Trials

Authors

  • Shaffi, Saeed Kamran, Raymond G. Murphy VA Medical Center, Albuquerque, New Mexico, United States
  • Wagner, Brent, Raymond G. Murphy VA Medical Center, Albuquerque, New Mexico, United States
Background

The frequency of biopsy-proven renal parenchymal diseases in the U.S. Southwest is unknown which is summarized in this study.

Methods

The University of New Mexico Kidney biopsy registry is a data repository from 2002 to 2019. We abstracted the primary diagnoses from the biopsy report with natural language processing and reviewed them to ensure data accuracy. We reported the initial primary diagnosis if the subsequent diagnoses were congruent in patients with multiple biopsies. Continuous and categorical data were reported as median (IQR) and n (%). We plotted time trends for each diagnosis.

Results

Of the 1204 unique native kidney biopsies, cancer and diabetic glomerulosclerosis were the most frequent diagnoses (Figure 1). The majority self-identified as Hispanic or American Indian. Biopsy frequency increased with time. Patients with cancer were the oldest at the time of biopsy while those with lupus nephritis were the youngest (p <0.001). A higher frequency of cancer and diabetic glomerulosclerosis was noted with time (Figure 2).

Conclusion

We used natural language processing to analyze kidney biopsy registry data in a predominantly Hispanic or American Indian cohort and identified disease frequency. This registry will facilitate the study of renal parenchymal disease's natural history and outcomes.

Demographic and clinical data at biopsy

Yearly N (Bars) and % (LOESS smoothed solidlines) of biopsies stratified on the primary diagnosis