Abstract: TH-PO305
Volumetric Accuracy Testing (VAT) of a Novel Patient-Centric Gravity-Based Automated Peritoneal Dialysis Cycler (GBC) vs. Conventional Pump-Based Cyclers (PBC)
Session Information
- Home Dialysis - I
November 02, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Sloand, James A., The George Washington University Milken Institute of Public Health, Washington, District of Columbia, United States
- Lindo, Steve J., Simergent, Oklahoma City, Oklahoma, United States
- Pendergraft, Rick, Simergent, Oklahoma City, Oklahoma, United States
Background
Safe and effective APD cycler function requires volumetric accuracy of fill and drain (F/D) volumes to accurately calculate achieved ultrafiltration (UF) critical to clinical outcomes in PD. PD fluid volume measurement in most contemporary APD cyclers is now pump, rather than gravity-based, partly due to unreliability of GBC load cells. However, PBCs contribute to device noise/sleep disruption and drain pain (in up to 47% of patients) from high suction pressures. VAT of a low cost, novel, newly engineered GBC designed to provide reliable F/D volumes was performed and values compared with reported F/D accuracy of conventional PBCs and another recently marketed GBC. In a recent blinded study, features of the novel GBC were rated far more favorably by PD patients & RNs than those of conventional PBCs.
Methods
VAT was performed collecting volume from both a Sartorius laboratory scale (“actual”) and the new GBC (“measured”). VAT was performed on 3 tubing sets with a patient bag at 2 bed heights (36” & 20”) and 2 F/D volumes (500ml & 3000ml). For both Fill & Drain, 5 cycles of 500ml (total 30 F/D cycles) and 3 cycles of 3000ml (total 18 F/D cycles) were tested. VAT was calculated as (measured-actual/actual) x 100%.
Results
Figures 1 & 2 show VAT results for Fill and Drain for 500ml & 3000ml F/D cycles at described bed heights. All 500ml Fills were within the required accuracy bounds of ±2%; all Drains were within the required accuracy bounds of ±3%. VAT for 3000mL volumes for both F/D was within ±1% volumetric error at both bed heights. Published F/D accuracy for FMC Liberty, Baxter HomeChoice, and FMC Silencia (GBC) are ±2%/±3%, ±2/±2%, and <±5%, respectively.
Conclusion
The novel low cost GBC with enhanced load cell technology & features previously demonstrated to be preferred by PD patients & RNs achieved F/D volumetric accuracy comparable to conventional PBCs and better than that of another recently marketed GBC. The new GBC has potential to significantly reduce drain pain, device noise & cost while maintaining UF accuracy.
Funding
- Commercial Support – Simergent LLC