Abstract: FR-PO907
The Effect of Dementia Screening Tests on Subsequent Kidney Function in the Elderly
Session Information
- Geriatric Nephrology
November 03, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Geriatric Nephrology
- 1300 Geriatric Nephrology
Authors
- Lee, So Young, Catholic University of Korea Yeouido Saint Mary's Hospital, Yeongdeungpo-gu, Seoul, Korea (the Republic of)
- Koh, Eun Sil, Catholic University of Korea Yeouido Saint Mary's Hospital, Yeongdeungpo-gu, Seoul, Korea (the Republic of)
- Bae, Eunjin, Gyeongsang National University Changwon Hospital, Changwon, Gyeongsangnam-do, Korea (the Republic of)
- Kim, Hyunsuk, Hallym University, Chuncheon, Gangwon-do, Korea (the Republic of)
- Hyun, Young Youl, Sungkyunkwan University, Jongno-gu, Seoul, Korea (the Republic of)
- Kwon, Soon hyo, Soonchunhyang University Hospital, Yongsan-gu, Seoul, Korea (the Republic of)
- Shin, Sung Joon, Dongguk University Medical Center, Goyang, Gyeonggi, Korea (the Republic of)
- Hong, Yu Ah, Catholic University of Korea Daejeon St Mary's Hospital, Daejeon, Korea (the Republic of)
- Chung, Sungjin, Catholic University of Korea Yeouido Saint Mary's Hospital, Yeongdeungpo-gu, Seoul, Korea (the Republic of)
Background
Previous cross-sectional and longitudinal studies have demonstrated that chronic kidney disease is associated with an increased risk for cognitive impairment at baseline and cognitive decline over time in older adults. However, it is unknown whether older people with subjective cognitive decline would be more likely to subsequently develop kidney dysfunction.
Methods
From the Korean National Health Insurance Service-National Elderly cohort database, this study included 111,846 subjects older than 60 years who completed the Korean Dementia Screening Questionnaire-Prescreening (KDSQ-P) or –Cognition (KDSQ-C) between 2007 and 2015. The association between subject cognitive decline and the incidence of kidney dysfunction was investigated during the follow-up.
Results
After adjusting for potential confounding factors, the risk of kidney dysfunction, defined as a decline of more than 30% in estimated glomerular filtration rate, was significantly lower in elderly without subjective cognitive decline based on both KDSQ-P results (HR=0.892, 95% CI 0.852-0.935, p <0.001) and KDSQ-C (HR=0.934, 95% CI 0.877-0.996, p=0.048) compared to those with subjective cognitive decline. The number of outpatient visits and admission as well as newly diagnosed cardio-metabolic disorders significantly increased in subjects with subjective cognitive decline after taking the dementia screening tests, indicating that a positive answer on the responses to KDSQ-P or KDSQ-C would have led to an increase in healthcare service utilization.
Conclusion
Subjects aged 60 years and older diagnosed as having suspicious cognitive dysfunction from dementia screening programs tend to have more preserved renal function probably through improvements in appropriate medical care with increased health concerns.