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Abstract: SA-PO1066

Recipient Obesity on Deceased Donor Kidney Transplant (DDKT) Outcomes: Overlooked Threats to Allograft Dysfunction and Delayed Graft Function (DGF)

Session Information

Category: Transplantation

  • 2102 Transplantation: Clinical


  • Hong, Suyeon, Uijeongbu Saint Mary's Hospital, Uijeongbu, Korea (the Republic of)
  • Chung, Byung ha, Seoul Saint Mary's Hospital, Seocho-gu, Korea (the Republic of)
  • Yang, Chul Woo, Seoul Saint Mary's Hospital, Seocho-gu, Korea (the Republic of)
  • Park, Woo Yeong, Keimyung University Dongsan Medical Center, Daegu, Korea (the Republic of)

As the prevalence of obesity increases globally, appreciating the effect of recipient obesity on graft outcomes is of increasing importance. However, the impact of recipient body mass index (BMI) on kidney transplant outcomes has been controversial. This study is designed to investigate the effect of recipient BMI on short and long-term outcomes of patients undergoing DDKT.


A total of 743 patients receiving deceased donor KT between 2005 and 2019 among 3 multi-centers were included in the study. Patients were divided according to their body mass index(BMI) into underweight (BMI<18.5,N=47), normal weight (BMI≧18.5 to BMI<25kg/m2,N=488), and obese (BMI≧25kg/m2,N=208) groups. Their clinicopathological characteristics, graft functions, graft survival rates and delayed graft function (DGF) were analyzed retrospectively.


Obesity was associated with deterioration of allograft function. Kidney function was significantly lower in obese group compared with underweight and normal BMI groups after 3 months to 3 years follow up after DDKT(3 months follow up p= 0.005, 1year p=0.009, 3year p=0.034). Multivariate analysis showed that recipient obesity (BMI≧25) was an important prognostic factor for DGF (OR1.24, 95% CI, 1.011-1.438, P=0.042). Though statistically insignificant, the death-censored graft survival rate tends to be negatively associated with recipients’ BMI level.


In conclusion, recipients’ obesity increases the risk of allograft dysfunction and it is found to be statistically significant prognostic factor for DGF. Therefore, appropriate risk-adapted information concerning BMI should be provided to patients and efforts to improve recipients’ obesity should be taken in advance to DDKT.

Figure 1. Allograft function & Recipients’ BMI.

Table1. Risk factors for delayed graft function(DGF)