ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

Abstract: FR-PO1139

Postdischarge All-Cause Mortality in COVID-19-Recovered Patients: The Impact of CKD

Session Information

  • COVID-19 - II
    November 03, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Coronavirus (COVID-19)

  • 000 Coronavirus (COVID-19)

Authors

  • Schittine Bezerra Lomba, Guilherme, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • da Silva, Pedro Henrique Abreu, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • Rosário, Natalia Fonseca, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • Medeiros, Thalia, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • Alves, Lilian Santos da Silva, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • Reis Almeida, Jorge, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
  • Lugon, Jocemir R., Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
Background

In Brazil, the COVID-19 burden was substantial, and risk factors associated with higher in-hospital mortality rates have been extensively studied. However, information on short-term all-cause mortality and factors associated with death in patients who survived the hospitalization period of acute SARS-CoV-2 infection is less abundant. We analyzed the 6-mo post-hospitalization mortality rate and possible risk factors of COVID-19 patients admitted from Mar/20 to Dec/20 in a single center in Brazil.

Methods

Retrospective cohort study focused on a 6-mo follow-up. Exclusion criteria were: death during hospitalization, transference to another hospital, and age under 18. We collected data from the charts of all hospitalized patients from Mar/20 to Dec/20 with positive RT-PCR test for SARS-CoV-2, a time when vaccination against the infection was not available and no variant other than the wild one had been identified in Brazil. The main outcome was death after hospitalization. Comorbidities and demographics were evaluated as risk factors.

Results

We studied 106 patients. The crude post-hospitalization death rate was 16.0%. The first 30 days of follow-up had the highest mortality rate. In a Cox regression model for post-hospitalization mortality, previous CKD (HR, 4.06, 95%CI 1.46 – 11.30) and longer hospital length of stay (HR 1.01, 95%CI 1.00 - 1.02) were the only factors statistically associated with death.

Conclusion

Substantial 6-mo all-cause mortality was observed. Within the 6-mo follow-up, a higher risk of death was observed for patients who had prior CKD and longer hospital length of stay. These findings highlight the importance of more intensive medical surveillance during this period.