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Abstract: FR-PO037

ToxiPedia: A Website Research and Education Tool on Uremic Toxins

Session Information

Category: Augmented Intelligence, Digital Health, and Data Science

  • 300 Augmented Intelligence, Digital Health, and Data Science

Authors

  • Tabibian, Noble Benjamin, University of California Los Angeles, Los Angeles, California, United States
  • Orantes, Carlos, Wearable Artificial Organs Inc, Los Angeles, California, United States
  • Gura, Victor, University of California Los Angeles, Los Angeles, California, United States

Group or Team Name

  • Wearable Artificial Organs.
Background

Mounting evidence suggests that current understanding of uremic toxicity is limited. As many different uremic toxins are being identified there is a need for research tools to better study, classify and analyze the different molecules implicated in uremic toxicity, their origin, chemical structure, metabolism, and ill effects. ToxiPedia, is an encyclopedic free access website, to be used as a tool to store all information on each toxin, its effects, chemical structure, metabolomic, proteomic, and toxicological classifications, and other pertinent information. It may also provide a continuously updated resource for researchers to study and analyze uremia. The clinical impact of uremic toxins will also be retrievable. The website aims to serve as an educational and research tool to improve renal replacement therapies that eliminate these toxins, improve the quality of life, and reduce morbidity and mortality.

Methods

The website is designed with a website generator to allow physicians and researchers to easily contribute to it. An advisory committee will validate the project to provide independent guidance and expert advice to improve the project before it is completed, along with a peer review process for every page. As new data on uremic molecules develops researchers can update and revise relevant pages to keep the website up to date.

Results

Online free acccess catalogue of Uremic Toxins allows retreiving all relevant information on Uremic Toxins.

Conclusion

This website may close current knowledge gaps and improve the accessibility of information on uremic toxins. It will also provide a much-needed resource to organize the large mass of emerging data on the uremic syndrome, causes, mechanisms, and complications. It is hoped that Toxipedia will contribute to more knowledge and better treatment of uremic toxicity.