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Kidney Week

Abstract: SA-PO1068

Association Between Pretransplant Dialysis Modality and Long-Term Graft Outcomes

Session Information

Category: Transplantation

  • 2102 Transplantation: Clinical

Authors

  • Seo, Young Kyeong, Inje University Busan Paik Hospital, Busan, Korea (the Republic of)
  • Kim, Taehee, Inje University Busan Paik Hospital, Busan, Korea (the Republic of)
  • Kim, Yunmi, Inje University Busan Paik Hospital, Busan, Korea (the Republic of)
  • Huh, Hyuk, Inje University Busan Paik Hospital, Busan, Korea (the Republic of)
  • Kim, Yeong Hoon, Inje University Busan Paik Hospital, Busan, Korea (the Republic of)
Background

previous systemic reviews have shown that peritoneal dialysis (PD) is associated with substantial improvements in patient survival and delayed graft function compared with hemodialysis (HD) treatment as a pretransplant modality, the association between pretransplant dialysis modalities and posttransplant outcomes remains controversial.

Methods

We retrospectively collected records from 773 kidney transplant recipients between January 2008 and October 2021 in 2 transplant
centers. We excluded recipients under the age of 18, 2nd or 3rd transplant recipients, and preemptive recipients. The final analysis
included 558 kidney transplant recipients(fig. 1)We examined graft survival across pretransplant modality.

Results

558 kidney transplant recipients were 47.5 years old and included 42% females and 28% diabetes. 407 recipients underwent HD, and
151 recipients underwent PD before transplantation.
The overall graft survival between pretransplant HD and PD showed no statistical difference (P=0.197)(Fig. 2).
pretransplant HD seemed to be favorable for graft survival over a long-term follow-up period of over 10 years.

Conclusion

Pretransplant modalities during the transition to a kidney transplant are not associated with graft survival.

Table 1. baseline characteristics of 558 KT recipients
 AllHDPDP value
Characteristics,
N (%)
558407151 
Age47.5±11.8
48±11.5
46±12.5
0.214
Female
236 (42)
167 (41)
69 (46)
0.322
DM158 (28)
127 (31)
31 (21)
0.02
HBP82 (15)
59 (15)
23 (15)
 
HBsAg40 (7)
33 (8)
7 (5)
0.249
CKD cause   0.148
DM132 (24)
103 (25)
29 (19)
 
Hypertension 82 (15)
59 (15)
23 (15)
 
GN136 (24)
91 (22)
45 (30)
 
PCKD24 (4)
20 (5)
4 (3)
 
Others13 (2)
11 (3)
2 (1)
 
Unknown164 (29)
116 (29)
48 (32)
 
Relations   0.609
LD197 (35)
141 (35)
56 (37)
 
DD359 (64)
264 (65)
95 (63)
 
ABOi tranplant 38 (7)
30 (7)
8 (5)
0.183
Waiting time, years4.5 (1.5, 7.4)
4.5 (1.3, 7.7)
4.4 (2.0, 6.8)
<0.001
Rejection episode445 (80)
330 (81)
115 (76)
0.021

LD, living donor; DD, deceased donor