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Kidney Week

Abstract: SA-PO571

Intradialytic Plantar Electrical Stimulation Boosts Mobility and Physical Activity in Frail Patients: A Randomized Controlled Trial

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Hamad, Abdullah Ibrahim, Hamad Medical Corporation, Doha, Qatar
  • Najafi, Bijan, Department of Surgery, Baylor College of Medicine, Houston, Texas, United States
  • Lee, Myeounggon, Department of Surgery, Baylor College of Medicine, Houston, Texas, United States
  • Ibrahim, Rania Abdelaziz, Hamad Medical Corporation, Doha, Qatar
  • Mathew, Mincy, Hamad Medical Corporation, Doha, Qatar
  • Ateya, Heba Mohamed, Hamad Medical Corporation, Doha, Qatar
  • Zitouni, Yoldez, Hamad Medical Corporation, Doha, Qatar
  • Rodriguez, Naima S., Department of Surgery, Baylor College of Medicine, Houston, Texas, United States
  • Beom, Jaewon, Department of Surgery, Baylor College of Medicine, Houston, Texas, United States
  • Al-Ali, Fadwa S., Hamad Medical Corporation, Doha, Qatar
Background

Frailty is notably pervasive in hemodialysis (HD) patients and contributes to diminished physical activity, poor quality of life, and mortality risk. Our study aimed to assess the efficacy of a targeted intradialytic plantar E-stim intervention to enhance mobility in frail diabetic HD patients.

Methods

Participants randomized into intervention group (IG, n=35) and control group (CG, n=33). IG received plantar E-stim treatment and CG had a non-operational device both for 1 hour with their HD sessions for 12-week period. To assess daily physical activity, participants wore a monitoring pendant for two consecutive days both at the onset of the study and following the 12-week intervention.

Results

The IG and CG showed no significant differences in age, sex, BMI, or frailty rates. Remarkable group x time interaction effects were noted in terms of physical activity (total standing transition: p=0.017; total walking transition: p=0.015) and mobility capacity (total steps: p=0.040) among frail patients. The IG demonstrated notable enhancements in standing (+18.12%, Cohen’s d=0.315) and walking transitions (+17.10%, Cohen’s d=0.476) from baseline to the 12-week mark. In contrast, the CG displayed a decrease in physical activity (Standing: -14.80%, Cohen’s d=0.281; Walking: -23.59%, Cohen’s d=0.365). Mobility capacity decline was less in IG (-3.48%, Cohen’s d=0.048), while CG saw a significant reduction (-52.85%, Cohen’s d=0.644).

Conclusion

This study highlights that intradialytic plantar E-stim substantially enhances both physical activity and mobility, particularly among frail HD patients. Given these findings, it is recommended that E-stim be integrated as an adjunctive measure to routine HD treatment.

Funding

  • Government Support – Non-U.S.