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Abstract: TH-PO223

Statewide Burden of CKD due to Hypertension (HTN) from 1990 to 2019 in the United States: Analysis for the Global Burden of Disease Study

Session Information

Category: Hypertension and CVD

  • 1602 Hypertension and CVD: Clinical


  • Gajjar, Rohan, John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States
  • Desai, Hardik, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India
  • Thajudeen, Bijin, Banner University Medical Center Tucson, Tucson, Arizona, United States
  • Jitta, Sahas Reddy, Mercy Hospital St Louis Area, Saint Louis, Missouri, United States
  • Rachapudi, Shasank, Kurnool Medical College, Kurnool, Andhra Pradesh, India
  • John, Jobby, Dr Somervell Memorial CSI Medical College and Hospital, Thiruvananthapuram, Kerala, India
  • Patel, Abhiraj, Our Lady of Fatima University College of Medicine, Valenzuela City, Manila, Philippines
  • Koppana, Viswaja, Mayo Clinic Minnesota, Rochester, Minnesota, United States

CKD due to HTN ranks as the 2nd leading cause of death among all causes of CKD in United States (US). We sought to assess the burden of CKD due to HTN within the US.


Using Global Burden of Disease methodology, prevalence, incidence, death, and disability-adjusted life year (DALYs) of CKD due to HTN assessed by age, sex, year from 1990-2019 for all resident in US.


The prevalence has shown a steady increase over the years, with the total number of cases rising from 1.5 million (95% uncertainty interval [UI]:1.4-1.7million) in 1990 to 2.8 million (95%UI:2.6-3.1million) in 2019. Simultaneously, the number of deaths has tripled, from 13,960 in 1990 to 43,329 in 2019. The highest Annual Percentage of Change (APC) in the age-standardized mortality rate (ASMR) was found in West Virginia(101%), Iowa(95%) and Minnesota(93%). For the ASIR, the highest rates were observed in Utah and California, both at 11%, with Iowa at 10%. The ASDR revealed West Virginia(87%), Iowa(81%), and Kentucky(80%) as the areas with the highest burdens. These conditions are more prevalent in older populations, significantly impacting that group.


CKD attributed to HTN has shown a rapid increase across the US, given the substantial APC in prevalence rose by 86%. From 1990-2019, the DALY numbers and the age standardized DALYs per 100,000 population caused by CKD due to HTN increased by 171% and 57%, respectively.