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Abstract: TH-PO278

Predictors of Hospitalization in Adolescents and Young Adults with ESKD

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Levy, Rebecca V., University of Rochester Medical Center, Rochester, New York, United States
  • Melamed, Michal L., Albert Einstein College of Medicine, Bronx, New York, United States
  • Hemmige, Vagish, Albert Einstein College of Medicine, Bronx, New York, United States
Background

Treatments for end-stage kidney disease (ESKD) include in-center dialysis, home dialysis, and transplant. Adolescents and young adults (AYA) are at increased risk for difficult disease course. Identification of risk factors for hospitalization may lead to changes in management.

Methods

We performed a secondary analysis of data in the US Renal Data System (USRDS). Included subjects were 16-24 years old at dialysis start 2010-2015 and had no previous history of kidney transplant. The combined outcome is time to first hospitalization. Analysis was by Cox proportional hazard modeling.

Results

Of the 4658 eligible subjects, 57% were male, 65% were white, and they had a mean age of 20.7 years (Table 1). Participants were followed for a median of 2.7 (2.6, 2.9) years during which there were 1963 hospitalizations. Multivariable Cox proportional hazards showed female sex, non-Hispanic ethnicity, dialysis catheter use, diabetic kidney disease, and lack of insurance were associated with increased risk of first hospitalization (Table 2).

Conclusion

Both demographic and potentially modifiable dialysis-related factors are associated with increased risk of hospitalization in AYA with ESKD.

Table 1. Baseline Characteristics

Table 2. Multivariable Hazard Ratios.