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Abstract: SA-OR29

Global Burden of CKD and Attributable Risk Factors in 38 Organization for Economic Cooperation and Development (OECD) Countries: Results from GBD 2019

Session Information

Category: CKD (Non-Dialysis)

  • 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Authors

  • Desai, Hardik, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India
  • Lieber, Joseph, Mount Sinai Health System, New York, New York, United States
  • Thajudeen, Bijin, Banner University Medical Center South, Tucson, Arizona, United States
  • Amin, Vishrant, Gujarat Medical Education and Research Society Medical College & Hospital Valsad, Valsad, Gujarat, India
  • Marsool, Mohammed Dheyaa Marsool, University of Baghdad, Baghdad, Baghdad , Iraq
  • Patel, Juhi, Gujarat Medical Education and Research Society Medical College & Hospital Valsad, Valsad, Gujarat, India
  • Kyada, Sumit, Gujarat Medical Education and Research Society Medical College & Hospital Valsad, Valsad, Gujarat, India
  • Lakkimsetti, Mohit, Mamata Medical College, Khammam, Telangana, India
  • Dhawan, Arushi, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
Background

CKD was the 8th leading cause of death in Organization for Economic Cooperation and Development(OECD) nations in 2019, accounting for 3.5% of all fatalities.

Methods

This study utilized the Global Burden of Disease methodology to analyze CKD incidence,mortality,disability-adjusted life years(DALYs), and associated risk factors in OECD countries.

Results

In 2019,OECD countries accounted for 35.06% of total global incident cases,27.7% of deaths, and 19.6% of DALYs attributed to CKD. Within the combined OECD countries,CKD incident cases increased by 103%, deaths by 179%, and DALYs by 120% from 1990-2019. Age-standardized incidence rates(ASIR) increased by 18%,ASDR by 29%,and ASMR by 37% between 1990-2019. In absolute counts, the United States(US) had the highest numbers with 1.7million incident cases (95%UI:1.5-1.8million),106,954 deaths(95,861–114,383),and 2.2million DALYs(2.1-2.4million) in 2019. Japan,Mexico,Germany,and Turkey followed suit. When comparing ASR, the US had a relatively lower ASIR(318) compared to countries such as Mexico(469) and Turkey(432) in 2019, but higher than Chile(316), Israel(299), and Japan(292).

Conclusion

CKD represents a significant burden in the 38 OECD countries. The high prevalence rates, association with cardiovascular disease, economic costs, health disparities, and impact on quality of life emphasize the need for comprehensive strategies to address CKD.