Abstract: TH-PO917
Dietary Sodium and Potassium Intake Estimations in Different Stages of CKD by Multiple 24-Hour Urine Collections
Session Information
- Health Maintenance, Nutrition, Metabolism - I
November 02, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Health Maintenance, Nutrition, and Metabolism
- 1500 Health Maintenance, Nutrition, and Metabolism
Authors
- Arici, Mustafa, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Baran, Berat, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Önder, Samed, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Karahan, Sevilay, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Bulut, Elif Ay?e, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Kinaci, Helin, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Dayanc, Fatma Sule, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Silleli, Onat, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Uysal, Ozan, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
- Emirsuleymanoglu, Elif, Hacettepe Universitesi Tip Fakultesi, Ankara, Ankara, Turkey
Background
Dietary sodium (Na) and potassium (K) intake in chronic kidney disease (CKD) patients can be calculated most accurately by multiple 24-hour urine (24hU) samples. While Na intake targets are known, optimal K intake according to different stages of CKD is not known. We aimed to examine how much Na intake met the guideline recommendations and the effect of K intake on serum K values in CKD patients.
Methods
This retrospective cohort study was based on 253 stable patients (who collected 5 or more 24hU between 2012-2022) at different stages of CKD. Clinical data was obtained through database of Hacettepe University Hospitals. 24hU sodium (24hUNa) and potassium (24hUK), serum Na, K and creatinine (Scre) values were analyzed. Generalized linear model for analysis of parametric variables was used.
Results
There was a total of 3493 urinary Na values from a mean of 13 collections in 253 patients. Mean 24hUNa was 134.3 +-70,5 mmol/d. Only 32.7% (n=1142) were below the recommended target of 100 mmol/d. There was a total of 1959 urinary K values from a mean of 14 collections in 135 patients. Mean 24hUK was 58,3 +-22 mmol/d. 24hUNa and 24hUK excretion according to the CKD stages was shown in Figure. There was no correlation between CKD stages and 24hUNa and 24hUK excretion. Scre values and 24hUNa values were inversely proportional, with beta:-0.001 and p:0.04. Scre values and 24hUK values showed an inverse correlation, with beta: -0.007 and p:0.00. When serum K values and 24hUK values were analyzed, beta is negligible, p:0.884. No statistically significant correlation was found between serum K values and 24hUK values.
Conclusion
24hUNa levels with recommended Na targets is present only in one third of the samples. The lack of relation with serum K and 24hUK values needs further studies to define an optimal K intake in different stages of CKD.