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Kidney Week

Abstract: SA-PO090

Outcomes of Intravenous Contrast Media on Patients with CKD: Systematic Review and Meta-Analysis

Session Information

Category: Acute Kidney Injury

  • 101 AKI: Epidemiology, Risk Factors, and Prevention

Author

  • Tawhari, Ibrahim, King Khalid University, Abha, Asir, Saudi Arabia

Group or Team Name

  • King Khalid University College of Medicine.
Background

Intravenous contrast media is frequently used in diagnostic and interventional procedures. Contrast-associated acute kidney injury (AKI) had been described as a complication associated with intravenous contrast media, which can lead to acute kidney injury and adverse clinical outcomes, especially in patients with underlying chronic kidney disease (CKD). However, this complication has been a subject of debate. The goal of this analysis is to evaluate the outcomes of intravenous contrast media use in patients with CKD.

Methods

A systematic search was conducted in PubMed, Scopus, ScienceDirect and Google Scholar for articles published from 2013 to March 2023. The reference lists of the included studies were also searched to retrieve possible additional studies.

Results

The meta-analysis included a total of 24 studies with a combined sample size of 278,908 participants. The pooled incidence of acute kidney injury in the OR was 0.85 (95% confidence interval [CI]: 0.75-0.95, P=0.005). In the association of dialysis and contrast media, had OR of 0.66(95%Cl: 0.26-1.69), p=0.39.

Conclusion

These findings suggest that contrast media use is not associated with a higher risk of acute kidney injury and dialysis needs in patients with chronic kidney diseases. More research is needed to fully understand the potential risks of contrast media used in this patient population.