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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

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Abstract: INFO05-TH

The Michigan O'Brien Kidney Translational Research Center: Transforming Translational Kidney Research Through Systems Biology

Session Information

  • Informational Posters - I
    November 02, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Augmented Intelligence, Digital Health, and Data Science

  • No subcategory defined


  • Bitzer, Markus, University of Michigan, Ann Arbor, Michigan, United States
  • Ju, Wenjun, University of Michigan, Ann Arbor, Michigan, United States
  • Lienczewski, Chrysta C., University of Michigan, Ann Arbor, Michigan, United States
  • Kretzler, Matthias, University of Michigan, Ann Arbor, Michigan, United States
  • Pennathur, Subramaniam, University of Michigan, Ann Arbor, Michigan, United States

Research on kidney diseases is being transformed by the rapid expansion and innovations in omics technologies. Analysis, integration, and interpretation of big data, however, has been an impediment to the growing interest in applying these technologies to understand kidney function and failure. Targeting this urgent need, the University of Michigan O’Brien Kidney Translational Core Center (MKTC) has focused services centered on enabling incorporation of systems biology approaches to address research priorities of center investigators. The Applied Systems Biology Core and its online analytical tools, Nephroseq and Nephrocell, have assisted hundreds of investigators around the world in approaches to the analysis of large transcriptomic datasets and other systems-level, biological studies of patients with kidney disease. The Administrative Core directs pilot and small grants and discount programs with the goal of helping new and established researchers utilize systems biological and translational research tools. The Enrichment Core provides infrastructure for educational and training programs and facilitates summer student immersive research experience. Together these cores provide a comprehensive translational research support for novel research into classification and treatment of kidney diseases. All interested academic investigators around the world are invited to make use of these services and to contact us for information and consultation.