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Abstract: TH-PO276

Factors Influencing Pre- and Post-Dialysis Central and Peripheral Blood Pressure in Dialysis-Dependent Veterans: A Single-Center Study

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Rasheed, Abdul Hannan A., Edward Hines Junior VA Hospital, Hines, Illinois, United States
  • Wadhwa, Anuradha, Edward Hines Junior VA Hospital, Hines, Illinois, United States
  • Kramer, Holly J., Edward Hines Junior VA Hospital, Hines, Illinois, United States
  • Vellanki, Kavitha, Edward Hines Junior VA Hospital, Hines, Illinois, United States
Background

Central aortic blood pressure (BP) is more reflective of cardiovascular health than peripheral BP. While it is hypothesized, central BP monitoring which detects minute changes in vessels is not suitable for dialysis patients due to stiff vessels, data on pre and post dialysis variations between central and peripheral BP is non-existent. We aimed to study the differences between pre and post dialysis central and brachial BP in patients and identify factors influencing any differences.

Methods

All patients receiving hemodialysis at Hines VA Hospital were approached between December 2021 and March 2022. Pre and post dialysis central aortic and brachial BP were obtained using ACTOR technology. Data collected included demographic characteristics, prescribed dialysis time and achieved ultrafiltration (UF). Mixed effects model was used for statistical analysis.

Results

A total of 51 patients participated in the study. Baseline characteristics are shown in Fig 1. Average difference of 2.6 mmHg is noted between pre and post dialysis brachial and central aortic systolic BP readings, post dialysis readings being higher than pre dialysis readings (Fig 2) after controlling for age, BMI, ethnicity, history of smoking, diabetes, peripheral vascular disease and coronary artery disease. Every 1 liter increase in UF is associated with a 1.35 mmHg difference in brachial vs. central aortic systolic BP.

Conclusion

In our single center study of veteran male dialysis population, for every liter of UF achieved, a 1.35 mmHg difference is noted in post dialysis brachial and central aortic systolic BP.

Fig 1: Baseline Characterisitics

Fig 2: Pre and Post Dialysis BP