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Kidney Week

Abstract: TH-PO327

Modifiable Physical Factors that Influence Physical Function for People Receiving Peritoneal Dialysis

Session Information

  • Home Dialysis - I
    November 02, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

  • 802 Dialysis: Home Dialysis and Peritoneal Dialysis

Authors

  • Tarca, Brett, University of South Australia Allied Health & Human Performance Academic Unit, Adelaide, South Australia, Australia
  • Jesudason, Shilpa, Central Adelaide Local Health Network, Adelaide, South Australia, Australia
  • Bennett, Paul N., University of South Australia Allied Health & Human Performance Academic Unit, Adelaide, South Australia, Australia
  • Wycherley, Thomas, University of South Australia Allied Health & Human Performance Academic Unit, Adelaide, South Australia, Australia
  • Ferrar, Katia, University of South Australia Allied Health & Human Performance Academic Unit, Adelaide, South Australia, Australia
Background

People receiving peritoneal dialysis experience physical function decline, impairing their ability to complete everyday activities, leading to poorer quality of life. Physical factors including cardiorespiratory fitness, muscle strength, physical activity and sedentary behaviour are associated with physical function, and considered modifiable, as they can be altered through intervention. However, little is known about the interrelationship between the factors and physical function or how these factors change over time in this cohort. This study aimed to explore modifiable physical factors that are associated with physical function, identifying which has the strongest influence, and explore temporal changes.

Methods

Adults receiving peritoneal dialysis underwent assessments for objective (Short Physical Performance Battery) and self-report (Short Form-36 Physical Function) physical function, cardiorespiratory fitness (six-minute walk), muscle strength (quadricep, bicep, abdominal, hand-grip strength), physical activity (accelerometry) and sedentary behaviour (inclinometery) on three occasions over a 12-month period (baseline, 6-months, 12-months).

Results

Eighty-two participants (mean age 61.4 years) underwent assessments. All modifiable physical factors were predominantly moderate to strongly associated with physical function at baseline. Through the observation period, cardiorespiratory fitness had the strongest and most consistent influence with every metre conferring a 0.08-unit (p <0.01) and 0.01-unit (p <0.05) increase in self-report and objective physical function score, respectively. Temporal changes were observed for modifiable physical factors with significant mean changes in cardiorespiratory fitness (-9.8%), quadricep strength (-5%), moderate-vigorous (-25.9%) and total (-16.2%) physical activity, and sedentary behaviour (+7.1%).

Conclusion

The results of this study indicate that cardiorespiratory fitness could be routinely monitored to detect risk of physical function decline and targeted through intervention to enhance physical function for people receiving peritoneal dialysis. Nevertheless, all factors should be considered when designing interventions to mitigate temporal changes and induce the numerous health benefits offered.