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Kidney Week

Abstract: SA-PO659

Factors Affecting Survival Rate in Diabetic Patients Who Underwent Immediate-Start Peritoneal Dialysis

Session Information

  • Home Dialysis - II
    November 04, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
    Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

  • 802 Dialysis: Home Dialysis and Peritoneal Dialysis

Authors

  • Cho, Hyunjin, Konkuk University Medical Center, Gwangjin-gu, Seoul, Korea (the Republic of)
  • Lee, Jee Young, Konkuk University Medical Center, Gwangjin-gu, Seoul, Korea (the Republic of)
  • Park, Jung Hwan, Konkuk University Medical Center, Gwangjin-gu, Seoul, Korea (the Republic of)
  • Jo, Young-Il, Konkuk University Medical Center, Gwangjin-gu, Seoul, Korea (the Republic of)

Group or Team Name

  • Division of Nephrology, Dept of Internal Medicine, Konkuk University Medical Center, Seoul, Republic of Korea.
Background

Peritoneal dialysis (PD) patients with diabetes mellitus (DM) are known to have poorer survival compared to PD patients without DM. However, there are few studies on risk factors associated with patient survival in diabetic end-stage renal disease (ESRD) patients underwent PD. The aim of this study was to identify factors independently associated with patient survival in diabetic ESRD patients who received immediate-start peritoneal dialysis (ISPD) without a break-in-period.

Methods

In this retrospective cohort study, 178 consecutive patients who started PD at Konkuk University Hospital from August 2005 to March 2023 were enrolled, and 144 patients with ISPD were finally analyzed. These patients were divided into the DM and the non-DM group. The primary outcomes were factors independently associated with patient survival in the DM group, estimated using a Cox proportional hazards regression model. Kaplan-Meier method was used to calculate patient survival rates.

Results

Among 144 patients, 93 (64.5%) had diabetes. The 1-, 5-, and 10-year patient survival rates of the DM and non-DM group were 97.6%, 86.9%, 35.1% and 98.4%, 92.1%, 65.6%, retrospectively. Compared to the non-DM group, the DM group had significantly higher age and body mass index (BMI), and significantly lower hemoglobin and serum albumin levels. However, only CVD was independently associated with patient survival in the DM group in univariate analysis, and this association was confirmed in multivariate analysis (Table 1).

Conclusion

Our study showed that CVD was the only factor independently associated with patient survival in ISPD patients with diabetes. Other factors such as age, BMI, hemoglobin, and serum albumin level did not appear to affect patient survival in diabetic ESRD patients who underwent ISPD without a break-in period.

Table 1. Multivariable Cox regression analysis for 10-year patient survival in the diabetic group