Kidney Week

ASN Midcareer Awards, Robert G. Narins Award, Belding H. Scribner Award, Barbara T. Murphy Award, State-of-the-Art Lecture Note: Continuing education credits are not being offered for this session.

Poster sessions will be posted on October 2. Note: Continuing education credits are not being offered for these sessions.

Exhibitor Spotlights (10:15-1:45)

This session presents compelling examples of population-specific kidney disease risk variants that arose as a consequence of local environmental adaptations in Africa. The session introduces modern tools of population genetics to identify disease variants under positive selection. Experts discuss the genetic complexities of kidney ...

Complement plays a central role in most glomerular diseases. Complement activation leads to glomerular accumulation of complement proteins and subsequent inflammation. New anticomplement drugs are now available to treat glomerular diseases associated with complement activation. This session addresses four disease entities: IgAN, me...

Recovery from dialysis-requiring AKI (AKI-D) requires careful decisions about when and how to step down kidney replacement therapy. However, clinicians often lack clear guidance on transitioning patients from CKRT to intermittent dialysis or safely discontinuing therapy as kidney function recovers. This session focuses on practical...

This session focuses on electrolyte disorders commonly encountered in patients with cancer, with an emphasis on therapeutic agent-induced electrolyte disorders and their management. In many instances, electrolyte disorders in cancer care can be addressed with basic knowledge of renal physiology. However, many novel therapeutic agen...

Climate change is transforming kidney care by driving more frequent and severe natural disasters, intensifying heatwaves and wildfires, and exposing the substantial environmental footprint of dialysis and nephrology practice. Patients with kidney diseases are uniquely vulnerable to climate-related disruptions, while dialysis care i...

This interactive session begins with an expert presenting cases, followed by several quiz questions for the audience. Topics include electrolytes, glomerulonephritis, kidney transplantation, CKD, and kidney replacement therapy.

Cardiovascular-kidney-metabolic (CKM) syndrome is a complex, interdependent disease continuum in which kidney dysfunction plays a central role. This session explores how kidney mechanisms drive CKM pathophysiology, complicate diagnosis, and shape therapeutic decision-making across the spectrum of CKD. The session examines emerging ...

High-Impact Clinical Trials - 2 Note: Continuing education credits are not being offered for this session.

Bone disease contributes to mortality in CKD. Diagnostic and treatment strategies are limited. This session focuses on the latest strategies and observations that inform and help improve skeletal care in CKD. Particular emphasis is placed on the detection and assessment of bone disease, the PTH-dependent effects of CKD on bone, and...

We continue to live through a period of historic change in kidney transplant care. This session examines some of the most significant developments in transplant policy over the past year; assesses the extent to which they affect patient access, quality of care, and health professionals' practice; and outlines future areas for impro...

This session highlights recent advances in multi-omics, spanning genomics, proteomics, metabolomics, and exposomics. Experts showcase innovative tools and study designs that enable integrated, multi-omics analyses to better capture biological complexity and environmental influences in kidney diseases. Emphasis is placed on how thes...

This session highlights the most impactful kidney research articles that have been recently published in these prestigious journals. To provide current information, the list of presentations will be available in September. Note: Continuing education credits are not being offered for this session.

Progressive kidney allograft dysfunction and graft loss remain major challenges in kidney transplantation. Emerging evidence implicates non-human leukocyte antigen (HLA) genetic variants and donor-recipient genomic mismatches as drivers of injury and fibrosis. Advances in single-cell and spatial multi-omics technologies provide cel...

Human genetics has transformed the understanding of diabetic kidney disease (DKD) by identifying risk loci that implicate specific biological pathways and cell types. This session integrates insights from genome-wide association studies, rare-variant analyses, and multi-omics profiling to connect genetic risk with molecular mechani...

This session highlights recent advances in understanding how distinct immune-cell subsets sculpt the injured kidney microenvironment and the regulatory pathways that govern these responses. Drawing on cutting-edge spatiotemporal mapping of immune-cell states in healthy and diseased kidneys, the session explores how dynamic immune p...

Several studies support the use of hemodiafiltration (HDF) for patients with ESKD. This session reviews recent studies and evidence on the potential benefits of HDF. Presentations explore which patients could derive the greatest benefit from HDF and discuss possible strategies and barriers to its wider adoption as a treatment for E...

This session highlights cutting-edge technologies and tools for identifying the central determinants of kidney injury outcomes. It provides in-depth insights into the emergence and evolution of microenvironmental niches that govern the fate of injured kidneys. In addition, the session emphasizes rigorous analytical approaches and s...

Human urine is often supersaturated, and kidney stones are common. Recent studies have improved our understanding of the factors that drive this supersaturation and modify the risk of kidney stone formation. Our understanding of monogenic and polygenic risks continues to expand. Recent evidence highlights the role of the gastrointe...

This session explores basic concepts and advanced lessons in physiology in the context of patients with extreme electrolyte disorders. Results that push the boundaries of survival typically challenge clinicians to consider the approach to pathophysiology, diagnosis, and care.

Women's kidney health is shaped by a complex interplay of biological, hormonal, and clinical factors. Integrating basic, translational, and clinical perspectives, this session examines how reproductive transitions, reproductive history, and exogenous hormone exposures influence kidney function across the lifespan. Emerging insights...

Dysregulated, or renin-independent, aldosterone production significantly contributes to hypertension, cardiovascular disease, and CKD. This session explores the mechanisms and pathophysiology of primary aldosteronism, with an emphasis on its effects on kidney health. Best practices for screening, diagnosing, and evaluating aldoster...

This session reviews the mechanisms of AKI (pseudo-AKI or hypercreatininemia) in patients hospitalized with heart failure. Experts discuss diagnostic challenges in detecting AKI, management dilemmas, and outcomes of patients who develop AKI. Novel management strategies for heart failure are also presented.

Congenital anomalies of the kidney and urinary tract (CAKUT) represent one of the most common causes of kidney diseases in children. This session provides a comprehensive, clinically focused overview for pediatric and adult nephrologists, researchers, and allied health professionals involved in the care of children diagnosed with C...

This session features complex kidney biopsy cases presented by renal pathologists in a mini-clinicopathologic conference, with a nephrologist as the clinical discussant. Case histories and biopsy images are posted on the ASN website for review before the meeting. Note: Continuing education credits are not being offered for this ...

Monoclonal gammopathy of renal significance (MGRS) presents unique therapeutic challenges at the intersection of nephrology and hematology. This session reviews contemporary approaches to clone-directed therapy, focusing on treatment indications, regimen selection, response assessment, and care coordination to improve kidney outcom...

The landmark discovery of autoantibodies in minimal change disease (MCD) and FSGS has advanced understanding of the underlying pathophysiology of these diseases. Translating these discoveries into clinical practice requires addressing key issues in measurement, diagnostic application, and therapeutic decision-making. This session r...

Over the past five years, interest in the kidney-brain axis, mechanisms of cognitive dysfunction in CKD, and potential novel therapeutics has grown exponentially. This session covers mechanisms of cognitive dysfunction and novel therapeutic strategies in CKD, with an emphasis on translational studies.

GLP-1 receptor agonists (RAs) have emerged as new drugs to slow the progression of kidney diseases in people with type 2 diabetes and CKD. New hormones have been combined with GLP-1 RAs to enhance their potency in lowering glucose and reducing body weight. These new combinations, referred to as multihormone receptor modulators, are...

This session provides a clinically focused update on cardiovascular-kidney-metabolic (CKM) complications in patients with cancer, highlighting mechanisms, risk stratification, and practical management strategies. Nephrology professionals are equipped with evidence-based approaches to manage hypertension and mitigate kidney and card...

This session explores the feasibility of home dialysis, both peritoneal dialysis (PD) and home hemodialysis (HD), for patients who are often considered ineligible and therefore denied the option of home dialysis. Evidence on the advantages and potential disadvantages of both home dialysis modalities is explored.

Oral abstract sessions will be posted on October 2. Note: Continuing education credits are not being offered for these sessions.

This session explores advances in kidney xenotransplantation, focusing on pig-to-human kidney transplants. Topics include outcomes of the first human xenotransplants, multi-omics profiling in gene-edited pig kidney recipients, and immunosuppression strategies for xenograft recipients. Physiological compatibility between pig kidneys...